An Evaluation of the Determination of the Lipophility of Apocynin and Diapocynin using HPLC
February 1st 2008This study evaluates the use of HPLC to estimate the log P (the octanol–water partition coefficient) of two compounds, apocynin and diapocynin. The paper will discuss the effects of an unexpected reversal of retention that occurred when these compounds were chromatographed with various amounts of methanol–water mobile phases.