Richard S. Rogers is a Principal Scientist in the Product and Analytical Department in Cell Therapy Development and Operations at Bristol Myers Squibb. At BMS, Richard leverages mass spectrometry to characterize viral vector and CAR-T cell drug product. He received his Ph.D. in Biochemistry and Molecular Biology from the Johns Hopkins University, USA.
Physicochemical Methods for Vectors and Ancillary Materials in Cellular and Gene Therapies
October 9th 2020Cellular and gene therapies (CGTs) have contributed significantly to the improvement of clinical outcomes for patients in the recent years. This paper discusses a range of physicochemical methods that play an important role in the difficult characterization of viral vectors, to meet the unique needs of CGT manufacturing process development, process and product characterization, and the quality control testing of these materials.