Barbara Kasprzyk-Hordern

This article gives an up-to-date commentary on chiral liquid chromatography coupled with mass spectrometry for the determination of pharmacologically active chiral compounds (cPACs) (including illicit drugs) in environmental matrices. Several applications are discussed to demonstrate the benefits of performing environmental analysis of cPACs at the enantiomeric level. Finally, future perspectives in this rapidly developing field of research are outlined.