YMC Product Profile
Chromatographers always seek to push the limits of HPLC columns to greater extremes to allow them to perform day-to-day with ever-changing pH, buffers and temperature ranges. The column for the laboratory of today must be suitable for harsh pH conditions in combination with high temperature ranges without sacrificing selectivity. Additionally narrow, symmetric peak shapes are necessary in order to cope with rapid analysis of demanding samples.
In order to meet these goals, YMC have developed a new particle technology. This is based on a multilayered particle produced via a well controlled granulation technology. The revolutionary production technique provides a multilayer silica-organic hybrid stationary phase, with an outstandingly narrow pore size and particle size distribution which, in turn, results in low back pressures and high loadability.
In addition, a proprietary multi-stage endcapping technique provides outstanding peak shapes, even for basic compounds. The innovative endcapping process also allows very high LC-MS sensitivity to be obtained which makes YMC-Triart an excellent first choice for residue analysis or any routine method development.
YMC-Triart columns are available with 1.9, 3 and 5 micron particles in various column sizes for (U)HPLC, inclusive Actus for fast semi-preparative HPLC.
Best of the Week: Food Analysis, Chemical Migration in Plastic Bottles, STEM Researcher of the Year
December 20th 2024Top articles published this week include the launch of our “From Lab to Table” content series, a Q&A interview about using liquid chromatography–high-resolution mass spectrometry (LC–HRMS) to assess chemical hazards in plastic bottles, and a piece recognizing Brett Paull for being named Tasmanian STEM Researcher of the Year.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
Determination of Pharmaceuticals by Capillary HPLC-MS/MS (Dec 2024)
December 19th 2024This application note demonstrates the use of a compact portable capillary liquid chromatograph, the Axcend Focus LC, coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis of pharmaceutical drugs in model aqueous samples.