Worldwide strategic alliance for non-chiral chromatography
Novasep and instrAction have entered into an alliance that will offer customers in the pharmaceutical industry a combination of instrAction?s proprietary API-selective stationary phases and Novasep?s purification capabilities and high performance chromatography technologies.
Novasep and instrAction have entered into an alliance that will offer customers in the pharmaceutical industry a combination of instrAction’s proprietary API-selective stationary phases and Novasep’s purification capabilities and high performance chromatography technologies. Together, the companies aim to develop and operate or supply optimized large-scale chromatography processes for purifying synthetic and semi-synthetic compounds.
“With the ever-increasing complexity of pharmaceutical compounds, traditional purification processes including crystallization, and even normal or reversed-phase chromatography, are often too expensive, and, worse, ineffective,” says René De Vaumas, executive vice president in charge of Novasep Synthesis’ business development.
“We believe that together, instrAction and Novasep will develop solutions that will provide great improvement in the purification of a number of pharmaceutical compounds,” said Dr Thomas Schwarz, CEO of instrAction GmbH. “Moreover, we believe that our joint approach with a single point of contact and streamlined project management will help reduce process development timelines.”
For more information on the companies visit their websites at www.novasep.com and www.instraction.com
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
