Waters and Chinese Pharmacopeia to Establish Joint Open Laboratory
Waters Corporation (Milford, Massachusetts) entered into an agreement with the Chinese Pharmacopoeia Commission (ChP) to establish a joint open laboratory.
Waters Corporation (Milford, Massachusetts) entered into an agreement with the Chinese Pharmacopoeia Commission (ChP) to establish a joint open laboratory. Scheduled to open before the end of 2014, the laboratory will focus on in-depth research of pharmacopoeia standards, development of testing methods, method validation, and basic and advanced technical training of pharmacopoeia detection methods. Both the ChP and Waters expect the laboratory to become one of the national technical support centers in Chinese pharmaceutical standards.
The Joint Open Laboratory will be located in the laboratory building of Beijing Zhendong Guangming Drug Research Institute (Beijing, China) and will be more than 1300 square feet in size. It will be outfitted with Waters’ chromatography and mass spectrometry systems, including, but not limited to, a range of Acquity UPLC systems, Acquity UPC2 systems, Xevo tandem quadrupole and time-of-flight mass spectrometers, and a natural products application solution with UNIFI software.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Frontage Laboratories Streamlines their Product Lifecycle Management with NuGenesis™ LMS
January 9th 2025Frontage laboratories wanted to improve the efficiency and quality of their operations and invest in ways to streamline their workflows. They implemented Waters NuGenesis™ Lab Management System (LMS) to progress their digital transformation journey and combine synergistic data, workflow, and sample management capabilities to support the entire product lifecycle from discovery through manufacturing.
The Intricacies of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
