Upfront Chromatography Develops Process for Whey Protein Isolation

Article

Upfront Chromatography A/S (Copenhagen, Denmark) announced the development of a single-step process for the isolation of the protein alpha-lactalbumin from whey.

Upfront Chromatography A/S (Copenhagen, Denmark) announced the development of a single-step process for the isolation of the protein alpha-lactalbumin from whey. The protein, which is naturally present in bovine and human milk, is used as a supplement in infant formulas. According to the company, the protein can be isolated using its expanded bed adsorption (EBA) columns. The process eliminates the need for heat treatment or clarification steps and enables preservation of the protein’s native structure. The columns reportedly operate at high flow rates with crude and unclarified feed stocks.

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André M. Striegel obtained his bachelor’s and Ph.D. in chemistry from the University of New Orleans. He performed postdoctoral research at the USDA’s National Center for Agricultural Utilization Research and then worked for a number of years in the chemical industry, for Solutia Inc. (now Eastman Chemical). From industry he went on to Florida State University, where he was assistant professor of both analytical and materials chemistry. Since 2011, he has been at the National Institute of Standards and Technology (NIST), where he is currently Scientific Advisor in the Chemical Sciences Division. André is the author of over 90 peer-reviewed scientific publications, lead author of the second edition of “Modern size-exclusion liquid chromatography,” editor of the book “Multiple detection in size-exclusion chromatography,” past associate editor of the Encyclopedia of Analytical Chemistry and, since 2015, editor of Chromatographia. He has received a number of awards, including the inaugural ACS-DAC Award for Young Investigators in Separation Science, and was also inaugural Professor in Residence for Preservation Research and Testing at the US Library of Congress. His interests lie principally in the area of macromolecular separations, both fundamental and applied.

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