Tuesday Afternoon Session Preview: Fundamentals of Peptide Fragmentation
Among the Tuesday afternoon oral sessions taking place on June 17 between 2:30 p.m. and 4:30 p.m. in Room 314-317 is ?Fundamentals of Peptide Fragmentation.? Yu Xia, of Purdue University (West Lafayette, Indiana), will preside.
Among the Tuesday afternoon oral sessions taking place on June 17 between 2:30 p.m. and 4:30 p.m. in Room 314-317 is “Fundamentals of Peptide Fragmentation.” Yu Xia, of Purdue University (West Lafayette, Indiana), will preside.
Bela Paizs, of Bangor University (Bangor, UK) will start the session at 2:30 p.m. with a presentation titled “IRMPD Spectroscopy of Ammonia Complexes of Peptide Fragments.”
Following Paizs, Chang Xue, of the University of Washington, Department of Chemistry (Seattle, Washington), will speak on “EDT Performance Comparison among Benzyl/Methl/ n-Butylguanidine-Tagged Peptides. Xue’s talk begins at 2:50 p.m.
At 3:10 p.m., Xing Zhang, of the University of California, Riverside (Riverside, California), will give a presentation titled “Radical Additions to Aromatic Residues in Peptides Facilitate Unexpected Side Chain and Backbone Losses.”
Helen J. Cooper, of the University of Birmingham (Birmingham, UK), will follow Zhang at 3:30 p.m. with a presentation on “Understanding the Electron Capture Dissociation of Phosphopeptides by Use of Ion Mobility Mass Spectrometry and Molecular Dynamics Simulations.”
Robert A. Everley, of the Harvard Medical School (Boston, Massachusetts) will present next, with a talk at 3:50 p.m. titled “Enhanced Loss of Phosphate from Isobarically Tagged Phosphotyrosine Peptides: Impact on Site Localization Assignment, Immonium Ion Formation and MS/MS Interpretation.
The session’s final presentation, starting at 4:10 p.m., will be given by Alexander Ebhardt, of ETH Zurich (Zurich, Switzerland). Ebhardt’s talk is titled “Applying Arginylation for Proteomics.”
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January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
