The current trend in laboratory equipment design is the miniaturization of laboratory instruments. Smaller-scale HPLC instruments offer benefits that cannot be matched by analytical-scale equipment, especially in the areas of portability, reduced fluid volumes, and reduced operating costs. Yet, the miniaturization of laboratory equipment has brought with it a unique set of challenges, including transferring methods to compact LC. Capillary LC expands the use of LC to applications not currently done using conventional LC in a wide array of application areas, including pharmaceutical, food and beverage, petrochemical, environmental, and oil and gas. Greg Ward, Axcend’s CEO wrote, “Customers want an HPLC system with a small footprint, low flow rates and green chemistry.” Join his podcast where he shares method transfer in these application areas.
Modern HPLC Strategies That Improve Retention and Peak Shape for Basic Analytes
August 16th 2024In high-performance liquid chromatography (HPLC), it is common for bases and unreacted ionized silanols on silica-based columns to cause irreproducible retention, broad peaks, and peak tailing when working with basic analytes. David S. Bell, Lead Consultant at ASKkPrime LLC offers innovative HPLC strategies that can help mitigate such issues.
Advancing Chromatographic Analysis: A Novel Composite Technology for SPE
July 22nd 2024Solid Phase Extraction (SPE) is vital for chromatographic analysis. However, traditional loose-packed SPE products struggle with channelling and inconsistent resin mass, resulting in poor recovery and reproducibility. Discover how innovative composite technology overcomes these challenges to transform sample preparation, ensuring reliable and sensitive chromatographic data.
Unveil the Power of Raman Spectroscopy for Real-Time Product Insight
May 20th 2024Raman spectroscopy is the ideal approach to compositional analysis and provides great versatility. In this Q&A, Tom Dearing, Senior Staff Scientist, and John Richmond, Senior Sales Manager, both at Thermo Fisher Scientific, provide an overview of the MarqMetrix All-In-One Process Raman Analyzer.