Mass spectrometry (MS) is considered to be the gold standard in chemical detection due to the speed, selectivity, sensitivity, and versatility of the method. A miniaturized, linear ion trap, mass spectrometer can rapidly detect and unequivocally identify chemical targets that reduce the cost to analyze field samples and, more importantly, eliminate gaps in security because actionable information can be obtained on timescales that are relevant for security personnel
Polysorbate Analysis in Biopharmaceutical Applications — A Snapshot of the Analytical Toolbox
An overview of different approaches for the qualitative and quantitative analysis of polysorbates.
Detailed Glycosylation Analysis of Therapeutic Enzymes Utilizing Comprehensive 2D-LC–MS
January 3rd 2025In this article, the use of comprehensive two-dimensional liquid chromatography (LC×LC) coupled to mass spectrometry (MS) for characterizing glycosylation of therapeutic enzymes is presented.