Tosoh Bioscience LLC
Tosoh Bioscience LLC is a major supplier of chromatography products worldwide, particularly to the pharmaceutical, biotechnology, and polymer industries.
Company Description
Tosoh Bioscience LLC is a major supplier of chromatography products worldwide, particularly to the pharmaceutical, biotechnology, and polymer industries. Our portfolio includes columns for all modes of separation as well as a dedicated HPLC system, the EcoSEC® GPC system, for semi-micro and high-throughput SEC measurements. The company distributes and supports products manufactured by our parent company, Tosoh Corporation, which has offices and manufacturing facilities in Japan. TSK-GEL® and TOYOPEARL® products are used for the analysis, isolation, and purification of proteins, peptides, polymers, DNA, oligonucleotides, antibiotics, and other small molecular weight compounds. Our products are known for their ability to withstand high pressure, their robust chemical stability, and their superior performance for the recovery, concentration, and purification of biomolecules and macromolecules.
Chief Chromatographic Techniques Supported
- Size exclusion
- Reversed-phase, normal phase (hydrophilic interaction)
- Ion exchange
- Hydrophobic interaction
- Affinity
Markets Served
Located in King of Prussia, Pennsylvania, Tosoh Bioscience LLC provides sales and service to pharmaceutical and biotechnology customers in North and South America.
Major Products/Services
Tosoh Bioscience offers a comprehensive line of TSK-GEL prepacked columns for each of the major chromatography modes, ToyoScreen® process development columns, as well as Toyopearl and TSK-GEL bulk resins for laboratory scale purifications and process chromatography.
Prepacked columns containing TSK-GEL media are designed for the analysis of proteins, peptides, other biopolymers, and low molecular weight compounds. The packings in the columns are either silica-based or polymer-based material, in particle sizes ranging from 2 µm to 20 µm. Columns are available in analytical through preparative sizes, in stainless steel, PEEK®, or glass.
ToyoScreen process development columns are available as an additional tool for convenient scale-up. These are easy-to use, pre-packed columns containing the popular Toyopearl resins and provide a convenient, low-cost method for the evaluation of Toyopearl ligand chemistries.
EcoSEC GPC system is a complete system for the analysis of polymers by GPC. The unit is ideal for semi-micro columns due to its low dead volume and as a result saves time, money, and valuable sample.
Facilities
Tosoh Bioscience LLC is located in King of Prussia, Pennsylvania. Supply chain offices are in Grove City, Ohio. European operations are in Stuttgart, Germany. Asia is served by Tosoh Corporation in Tokyo, Japan and Shanghai, China. Products are manufactured by Tosoh Corporation in Japan.
Tosoh Bioscience LLC
3604 Horizon Drive
Suite 100
King of Prussia, PA 19406
TELEPHONE
(484) 805-1219
(800) 366-4875
FAX
(610) 272-3028
WEB SITE
NUMBER OF EMPLOYEES
35
YEAR FOUNDED
1987
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Metabolomics Analysis of Low Birth-Weight Infants Using UHPLC-MS/MS Following Lipid Emulsion
January 10th 2025A recent study aimed to directly compare the changes in serum metabolites among very low birth-rate (VLBW) infants following the administration of the soybean oil-based lipid emulsion and soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) lipid emulsion using untargeted metabolomics techniques.
Analyzing New Drug Modalities: An ISC 2024 Interview with Kelly Zhang
January 10th 2025At ISC 2024 in Liverpool, United Kingdom, LCGC International interviewed Kelly Zhang of Genentech about her work analyzing new drug modalities, such as mRNA, oligonucleotides, peptides, and cell and gene therapies.
