Founded on state-of-the-art Core Enhanced Technologyâ„¢ and utilizing vast experience in phase bonding and packing, Thermo Scientificâ„¢ Accucoreâ„¢ HPLC columns provide a unique chromatography solution to enhance laboratory workflow and efficiency. Available in a wide range of stationary phase selectivities and compatible with almost any instrument, these columns provide an excellent return on investment.
Founded on state-of-the-art Core Enhanced Technology™ and utilizing vast experience in phase bonding and packing, Thermo Scientific™ Accucore™ HPLC columns provide a unique chromatography solution to enhance laboratory workflow and efficiency. Available in a wide range of stationary phase selectivities and compatible with almost any instrument, these columns provide an excellent return on investment.
Accucore HPLC Columns
Containing solid core particles, which are engineered to a diameter of 2.6 µm and a very narrow particle size distribution; Accucore HPLC columns allow high speed, high resolution separations, with back pressures significantly lower than those associated with UHPLC.
Accucore HPLC Columns for Biomolecules
The range of Accucore HPLC columns packed with 150 Å pore diameter particles allows biomolecule separations to benefit from the superb resolution and high speed enabled by Core Enhanced Technology™.
Accucore XL HPLC Columns
Using 4 μm solid core particles, Accucore XL HPLC columns allow users of conventional HPLC methods to enjoy performance far beyond that of columns packed with 5 μm, 4 μm or even 3 μm fully porous particles.
Learn moreThermo Fisher ScientificTudor Road, Manor Park, Runcorn, Cheshire WA7 1TA, UKTel: +44 (0) 1928 534110Website:www.thermoscientific.com/chromatographyEmail:lcgc.consumables@thermofisher.com
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Metabolomics Analysis of Low Birth-Weight Infants Using UHPLC-MS/MS Following Lipid Emulsion
January 10th 2025A recent study aimed to directly compare the changes in serum metabolites among very low birth-rate (VLBW) infants following the administration of the soybean oil-based lipid emulsion and soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) lipid emulsion using untargeted metabolomics techniques.
Analyzing New Drug Modalities: An ISC 2024 Interview with Kelly Zhang
January 10th 2025At ISC 2024 in Liverpool, United Kingdom, LCGC International interviewed Kelly Zhang of Genentech about her work analyzing new drug modalities, such as mRNA, oligonucleotides, peptides, and cell and gene therapies.