Therapeutic oligonucleotide analysis without ion-pair reagents (Nov 2024)

Trace-level analysis of VOCs in a tomato product using headspace extraction with large volume preconcentration (LVP) and multi-step enrichment (MSE)

This study demonstrates the Centri® sample extraction and enrichment platform’s unique multi-step enrichment feature to enhance the discovery of trace-level, packaging-derived contaminants in food and beverage samples by GC–MS.

Efficient separation N-glycans and isomers by HPAEC and quantification with Pulsed Amperometric Detection (PAD) and MS for identification.

This study demonstrates highly sensitive detection of residual fumigants in seeds and spices using MSE–HS–trap with GC–MS, achieving detection limits as low as 0.0018 mg/kg, well below EU regulatory limits. Excellent linearity (R² > 0.99), reproducibility, and throughput (40 samples/day) are achieved. Enhanced sensitivity with single-ion-monitoring (SIM) is also demonstrated for ethylene oxide and 2-chloroethanol.

Various samples, ranging from short-chain FOS to long-chain inulin including heterogenous blends of inulin-type fructans, can be easily analyzed using HPAEC-PAD.

Separation of oligo- and polysaccharides in honey up to DP40 within 25 minutes run time, enabling fast profiling of fraudulent/adulterated honey.