The Future of Chromatography Sample Preparation: Trends in Solid phase Extraction Methods
Solid Phase Extraction (SPE) is so reliable…said no one ever! Although there are many tips, tricks and recommendations to overcome common challenges with SPE, one solution lies within the structure of products used to carry out this method. In this episode of LCGC’s Dedicated Dialogue, James Edwards from Porvair Sciences introduces SPE, its evolution and its future with insights from a manufacturing and product development perspective on SPE for sample preparation workflows can be improved and make life easier in the lab for researchers.
Determining the Link Between Prenatal Cannabis Use and Symptoms of Depression Using LC–MS/MS
April 16th 2025Researchers investigating the relationship between cannabis use during pregnancy and depressive symptoms—and whether continued use beyond the first trimester or higher levels of use were linked to increased symptoms—used liquid chromatography–tandem mass spectrometry (LC–MS/MS) to confirm the presence of 11-nor-9-carboxy-delta-9-tetrahydrocannabinol (THC-COOH) in urine samples.
Common Challenges in Nitrosamine Analysis: An LCGC International Peer Exchange
April 15th 2025A recent roundtable discussion featuring Aloka Srinivasan of Raaha, Mayank Bhanti of the United States Pharmacopeia (USP), and Amber Burch of Purisys discussed the challenges surrounding nitrosamine analysis in pharmaceuticals.
Identifying PFAS in Alligator Plasma with LC–IMS-HRMS
April 15th 2025A combination of liquid chromatography ion mobility spectrometry, and high-resolution mass spectrometry (LC–IMS-HRMS) for non-targeted analysis (NTA) was used to detect and identify per- and polyfluoroalkyl substances (PFAS) in alligator plasma.
