The 15th Multidimensional Chromatography Workshop

The 15th Multidimensional Chromatography Workshop is a free event involving keynote and contributed presentations, a poster session, and discussion groups on all multidimensional techniques, and will be held in-person on the campus of California State University, Los Angeles, from January 10th to the 12th, 2024. The workshop welcomes both experts and new users to the field for training, networking, and sharing the latest trends. Keynote lecturers will present on major trends in both multidimensional gas chromatography (GC) and multidimensional liquid chromatography (LC), offering insights from both academic and industry research perspectives.

Participants will be able to join guided discussions intended to stimulate discussion on key areas of the field. The full program will include popular topics including modulation technologies, data analysis, and applications in different industries and research areas. Additionally, the program features a poster session, and presenters will have the chance to compete for two poster awards:

1. Multidimensional GC Poster Award—Sponsored by the American Chemical Society’s Subdivision on Separations Chemistry and Chromatography—$250 USD Award
2. Multidimensional LC Poster Award—Sponsored by the American Chemical Society’s Subdivision on Separations Chemistry and Chromatography—$250 USD Award

Keynote Lectures

This year, the workshop will highlight the work of four keynote speakers. The speakers come to us with experience in either multidimensional GC or multidimensional LC, and they represent academic, industry, and government sectors. In addition, we have asked all the keynote speakers to address the following questions in their presentations to get their perspective on the evolution of multidimensional chromatography:

• What sparked your interest in multidimensional chromatography?
• What was the moment you were convinced that multidimensional chromatography was a valuable solution to adopt?
• What is the biggest challenge facing the field of multidimensional chromatography?
• What is the most interesting application of multidimensional chromatography you have seen in the last year?
• Why does multidimensional chromatography matter?

Keynote Speakers

Sarah Prebihalo, Ph.D. - United States Food and Drug Administration

Presentation Title: From Research to Routine Analysis – The Role of GC×GC in the Regulatory Space

Sarah Prebihalo is a Chemist at the U.S. Food and Drug Administration in Maryland as a part of the Office of Regulatory Science at the Center for Food Safety and Applied Nutrition (CFSAN). Sarah worked as a laboratory technician at Procter and Gamble for 2 years after obtaining her bachelor’s in chemistry, before moving to Pennsylvania to obtain her master’s degree in forensic chemistry at Penn State. In 2015, she began working towards her Ph.D. in Chemistry at the University of Washington in Seattle, which she obtained in 2020. After completing a two-year postdoctoral fellowship at the U.S. Food and Drug Administration, she transitioned to her current role as Chemist and is involved in non-targeted method development for foods and dietary supplements using GC×GC. ​

Qinggang Wang, Ph.D. – Bristol-Myers Squibb

Presentation Title: Two-Dimensional Liquid Chromatography for Small Molecule Pharmaceutical Analysis – More Knowledge in Less Time

Qinggang Wang is a Scientific Director in Chemical Process Development in Bristol-Myers Squibb Company. He received his B.S. in Chemistry and Ph. D. in Analytical Chemistry from Tsinghua University, Beijing, China. His work has been focused on CMC analytical supports for various projects within BMS portfolio, including small molecules, synthetic peptides and oligonucleotides. He has authored or co-authored 18 peer-reviewed publications and three book chapters in analytical science. His research focuses on application of novel analytical techniques to pharmaceutical analysis. He is the recipient of BMS BMSIARC award for outstanding achievement in analytical science in 2019.

Thomas Bouvarel, Ph.D. - Genentech

Presentation Title: On-Line Multi-Dimensional LC/MS: The Next-Generation Tool for Real-Time Monitoring of Antibody Quality Attributes in Biopharmaceutical Processes

Thomas Bouvarel is currently Senior Scientist in the Department of Analytical Protein Chemistry at Genentech (a member of Roche group) in South San Francisco, California. He received his Ph.D. in analytical chemistry from Sorbonne University, France. After completing a postdoctoral fellowship at the University of Geneva, Switzerland, he joined Genentech. His research involves the development and implementation of novel multi-dimensional liquid chromatography methodologies for the characterization and on-line monitoring of biomacromolecules.

Gwen O’Sullivan, Ph.D. - Mount Royal University

Presentation Title: From Wildfire Origins to Courtroom Verdicts: Exploring Arson Investigations with Multidimensional Chromatography

Gwen O’Sullivan is an environmental chemist specializing in Environmental Forensics, particularly in wildfire forensics, arson investigation, air monitoring, and risk assessment. She combines analytical chemistry and environmental science to study the origins and behavior of pollutants and their environmental impacts.Over the course of her career, in industry, consultancy, and academia, Gwen has developed technical expertise in the areas of wildfire forensics, environmental chemistry, environmental forensics, air quality, and contaminated land and groundwater. She has worked environmental forensic investigations involving compounds of concerns including ignitable liquids, drilling fluids, petroleum hydrocarbons, polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins and dibenzofurans, methane, and nitrates. She has also authored numerous scientific articles, edited book series, and successfully competed for research grants both nationally and internationally.​

Focus Groups

This year, the workshop will host guided discussions focused on two topics gaining importance in the field of multidimensional chromatography. This will also be an opportunity for individuals to interact more informally to learn more about certain topics, or to contribute their expert opinions. Guided discussions will be led by experts in multidimensional separations.

Discussion Topic 1: Advantages and Limitations of GC×GC in Government and Industrial Laboratories

Multidimensional separations are commonly used in government and industrial laboratories, however they are not yet widely accepted due in part to perceptions about complexity of the technique, and lack of standardized and validated methods. This discussion will be focused on strategies to elevate multidimensional separations in government and industrial laboratories.

Discussion Topic 2: Development of a System Performance Standard Reference Test Mixture for Comprehensive Two-Dimensional Gas Chromatography

GC×GC system performance is influenced by many parameters, including modulator type, column set, detection method, and data processing software. This discussion will be focused on the development of a standard test mixture that can be used to compare GC×GC system performance across instruments and laboratories.

Registration is completely free of charge and can be completed at www.multidimensionalchromatography.com. We hope that you will join us for this exciting event, whether you are looking to find out what multidimensional chromatography is all about, looking to improve your skills in multidimensional separations, or hoping to improve your network in the field of multidimensional chromatography.

Conference Committee

Katelynn A. Perrault Uptmor is at William and Mary University in Williamsburg, Virginia, USA.

Pierre-Hugues Stefanuto is at University of Liège in Liege, Belgium.

Dwight Stoll is at Gustavus Adolphus College in St. Peter, Minnesota, USA.

Petr Vozka is at California State University in Los Angeles in California, USA.

Website: www.multidimensionalchromatography.com