See the Poroshell 120 Video!
Now you can get the benefits of exceptional efficiency ?more speed and more resolution ? on your conventional HPLC instruments.
Now you can get the benefits of exceptional efficiency - more speed and more resolution - on your conventional HPLC instruments. Poroshell 120 columns give you speed and resolution like a sub-2 μm column with up to 50% less back pressure - usually less than 400 bar.
In this video, Ron Majors and John Henderson demonstrate how to leverage Poroshell 120 on your conventional HPLC instrument, for optimal results. There are downloadable notes with chromatograms and exhibits, too.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
