A common cause of high back pressure, split peaks, broad peaks, baseline noise, baseline drift, and loss of resolution is contaminants. All mobile phases contain some chemical contaminants or micro particulates, from the sample, solvent, or wear on the polymeric seals of the pump or injector. These contaminants can clog frits, irreversibly bind to columns, degrade performance, and even damage the flow cell. An easy solution, SecurityGuard is a universal column protection system designed to effectively (and inexpensively), protect your valuable columns, from the damaging effects of chemical contaminants, without altering your chromatographic results.