DSM Biologics, a business unit of DSM Pharmaceutical products, has announced that it has reached an agreement for the acquisition of the assets and associated business of the Rhobust technology from Upfront Chromatography A/S.
DSM Biologics, a business unit of DSM Pharmaceutical products, has announced that it has reached an agreement for the acquisition of the assets and associated business of the Rhobust technology from Upfront Chromatography A/S.
According to the companies, the technology is capable of performing high titre and high density cell culture processes, which allows for stable expanded bed adsorption chromatography. The cells are separated in one step while capturing the protein/antibody of interest; during the expanded bed adsorption chromatography process the cell suspension passes through the column and the product is adsorbed either on Protein A or on mixed mode ligand beads. This leads to less handling and shorter process times.
In a statement, Karen King, president of DSM Biologics commented, “The acquisition of the Rhobust technology is an important addition to the portfolio of DSM Biologics. The Rhobust technology combined with DSM’s proprietary XD technology will provide an integral package combining high titre, high yield processing with efficient downstream processing leading to lower manufacturing costs.”
As a result of the acquisition, DSM Biologics will gain all rights for the commercialization of the technology in various fields, including the pharma industry.
The technology will lead to further innovation in the downstream processing for the manufacturing of recombinant proteins and antibodies. DSM Biologics will continue to support all existing clients for this technology. The parties have agreed to not disclose financial details.
For more information about this technology visit www.dsm.com
HPLC 2025 Preview: Fundamentally Speaking (Part 1)
May 13th 2025Michael Lämmerhofer from the Institute of Pharmaceutical Sciences, University of Tübingen, Germany, spoke to JFK Huber Lecture Award winner of 2024 Torgny Fornstedt, professor in analytical chemistry and leader of the Fundamental Separation Science Group, Karlstad University, Sweden, about his pioneering work in high performance liquid chromatography (HPLC) with a focus on fundamentals and industrial applications.
Reversed-Phases for LC Deliberately Doped with Positive Charge: Tips and Tricks for Effective Use
May 13th 2025In this month's edition of LC Troubleshooting, Dwight Stoll and his fellow researchers discuss both the benefits (improved peak shape/loading) and challenges (excessive interaction) associated with charge-doped reversed-phase (RP) columns for both analytical and preparative separations.
Determining Ways to Protect Honeybee Colonies with GC–MS
May 13th 2025A study conducted by the Agriculture Research Centre of Giza, Egypt, and Jilin Agricultural University in China, evaluated the efficacy of stinging nettle extract, nettle smoke, and formic acid in the controlling of Varroa mites, a major threat to honeybee colonies, with a focus on mite infestation reduction, honeybee mortality, and biochemical responses. Gas chromatography–mass spectrometry (GC–MS) was used to identify key bioactive compounds in the stinging nettle extract.