Researchers Discover Tuberculosis in 9,000-year-old skeleton using HPLC
Research by scientists from University College London (UCL) and Tel Aviv University shows that the tuberculosis infection is 3,000 years older than was previously imagined and that TB in people evolved before bovine TB.
Research by scientists from University College London (UCL) and Tel Aviv University shows that the tuberculosis infection is 3,000 years older than was previously imagined and that TB in people evolved before bovine TB. Professor Israel Hershkovitz of Tel Aviv University noticed lesions that are a sign of TB in the bones of skeletons discovered at Alit-Yam, a 9,000 year-old pre-pottery Neolithic village. Dr. Helen Donoghue and Dr. Mark Spigelman, of the UCL Centre for Infectious Diseases & International Health, led an international collaborative team through analysing the bones using scientific techniques to reveal DNA and cell wall lipids from mycobacterium tuberculosis, the principal agent of human TB. The DNA in the excavated bones was sufficiently well-preserved for molecular typing to be carried out and the analysis of the bacterial cell wall lipids by high performance liquid chromatography provided evidence of tuberculosis.
LCGC’s Year in Review: Highlights in Liquid Chromatography
December 20th 2024This collection of technical articles, interviews, and news pieces delves into the latest innovations in LC methods, including advance in high performance liquid chromatography (HPLC), ultrahigh-pressure liquid chromatography (UHPLC), liquid chromatography–mass spectrometry (LC–MS), and multidimensional LC.
Next Generation Peak Fitting for Separations
December 11th 2024Separation scientists frequently encounter critical pairs that are difficult to separate in a complex mixture. To save time and expensive solvents, an effective alternative to conventional screening protocols or mathematical peak width reduction is called iterative curve fitting.
Mobile Phase Buffers in Liquid Chromatography: A Review of Essential Ideas
December 11th 2024In this installment of "LC Troubleshooting," Dwight Stoll discusses several essential principles related to when and why buffers are important, as well as practical factors, such as commonly used buffering agents, that are recommended for use with different types of detectors.
The Chromatographic Society 2025 Martin and Jubilee Award Winners
December 6th 2024The Chromatographic Society (ChromSoc) has announced the winners of the Martin Medal and the Silver Jubilee Medal for 2025. Professor Bogusław Buszewski of Nicolaus Copernicus University in Torun, Poland, has been awarded the prestigious Martin Medal, and the 2025 Silver Jubilee Medal has been awarded to Elia Psillakis of the Technical University of Crete in Greece.
