The Pittcon Editors? Awards have been awarded to the products judged to be the most innovative at the show. The gold award was shared by the LECO Citius LC–HRT and the WITec True Surface Microscopy Raman spectrometer.
The Pittcon Editors’ Awards have been awarded to the products judged to be the most innovative at the show. The gold award was shared by the LECO Citius LC-HRT and the WITec True Surface Microscopy Raman spectrometer.
The LC HRT is an LC and high resolution TOF-MS system, which incorporates Folded Flight Path that the company claims provides full-range mass spectra at speeds of over 100 spectra per second, and resolutions of up to 100 000 with high-performance mass accuracy. The system provides ESI, APCI and desorption electrospray ionization sources to complement its MS capabilities and dynamic range.
The True Surface Microscopy Raman spectrometer is reported to feature an integrated sensor for optical profilometry. According to the company, large-area topographic coordinates from the profilometer measurement can be precisely correlated with the large-area confocal Raman imaging data.
The silver award went to EMD Millipore for the Samplicity Filtration system for HPLC sample prep, which the company claims provides a convenient, high throughput alternative to syringe-tip filters when preparing samples for chromatography.
Finally bronze was awarded to AstraNet for the Astra Gene Spectrophotometer's patented sample holder, which is claimed to enable measurements to be taken, and recovered, direct through a pipette tip on volumes as low as 2 µL.
For more on the conference visit www.pittcon.org
Detailed Glycosylation Analysis of Therapeutic Enzymes Utilizing Comprehensive 2D-LC–MS
January 3rd 2025In this article, the use of comprehensive two-dimensional liquid chromatography (LC×LC) coupled to mass spectrometry (MS) for characterizing glycosylation of therapeutic enzymes is presented.
Advancing Gene Therapy: Enzyme Selection for Effective RNA Oligonucleotide Mapping
New gene therapy modalities, such as CRISPR guide RNA (single guide ribonucleic acid [sgRNA]) and messenger RNA (mRNA), continue to make progress in both primate and first-in-human trials. As this progress builds, the industry remains accountable for characterizing these molecules to meet the requirements of regulatory authorities.