Online SPE and HPLC in one
Spark Holland Product Profile
The Spark Holland Symbiosis™ Pico is a compact, affordable and versatile online SPE System embedded in a high-end HPLC system offering superb analytical performance and improved workflow. The system features a fully programmable high performance injector which handles sample volumes from 10μl up to 10ml, adding, mixing and diluting samples prior to analysis. The high pressure gradient LC pump comes with a four channel solvent selector for each pump, facilitating the use of multiple LC solvents and gradients. Combined with the optional column oven with integrated six port LC column selector, a large variety of LC conditions can be selected in consecutive unattended runs, giving the highest degree of flexibility both for method development and routine use. In addition, Symbiosis Pico has an integrated sample preparation system that offers all the advantages of online SPE, such as higher assay sensitivity, analysis of small sample injection volumes, no sample loss, minimal carry-over and robust and reproducible assays, while reducing method development time. The new multi dimensional SPE mode allows the use of two different extraction mechanisms on two separate disposable SPE cartridges in one sample run, resulting in the highest possible sample clean up.
Contact:
sales@sparkholland.comwww.sparkholland.com
New TRC Facility Accelerates Innovation and Delivery
April 25th 2025We’ve expanded our capabilities with a state-of-the-art, 200,000 sq ft TRC facility in Toronto, completed in 2024 and staffed by over 100 PhD- and MSc-level scientists. This investment enables the development of more innovative compounds, a broader catalogue and custom offering, and streamlined operations for faster delivery. • Our extensive range of over 100,000 high-quality research chemicals—including APIs, metabolites, and impurities in both native and stable isotope-labelled forms—provides essential tools for uncovering molecular disease mechanisms and exploring new opportunities for therapeutic intervention.
New Guide: Characterising Impurity Standards – What Defines “Good Enough?”
April 25th 2025Impurity reference standards (IRSs) are essential for accurately identifying and quantifying impurities in pharmaceutical development and manufacturing. Yet, with limited regulatory guidance on how much characterisation is truly required for different applications, selecting the right standard can be challenging. To help, LGC has developed a new interactive multimedia guide, packed with expert insights to support your decision-making and give you greater confidence when choosing the right IRS for your specific needs.
