The New Agilent 6490 Triple Quadrupole LC/MS - Clearly Better from A to Z
The new 6490 LC/MS provides the highest level of sensitivity for a wide range of critical applications such as environmental, food testing, and pharmaceutical analyses.
From attogram limits of quantitation to zeptomole sensitivity, the new Agilent 6490 Triple Quadrupole LC/MS delivers unprecedented analytical performance for your most rigorous, regulated assays. But that’s just the beginning. The Agilent 6490 LC/MS is a truly comprehensive solution, from A to Z.
Advanced iFunnel technology revolutionizes atmospheric sampling and helps reduce detection limits to an all-time low
Unmatched acquisition and data analysis speed lets you take full advantage of the super-fast separations provided by Agilent’s 1290 Infinity LC
The industry’s most advanced MRM software enables fast, accurate LC/MS analysis of complex samples—ideal for large, multi-analyte assays from fast LC separations
Maximum uptime and simplified operation boost your lab’s productivity
Seamless integration with Agilent HPLC-Chip/MS provides ultrasensitive quantitation of small volume samples
Learn more about the industry-leading sensitivity of the 6490 Triple Quadrupole LC/MS - get a FREE iFunnel Kit, including “The Ion Funnel: Theory, Implementations, and Applications,” plus additional literature. Visit www.agilent.com/chem/atoz
Liquid Chromatography to Analyze Vitamin D Proteins in Psoriasis Patients
January 21st 2025Can a protein involved in delivering Vitamin D to target tissues have an altered serum profile in psoriasis patients with cardiovascular disease? Researchers used liquid chromatography (LC) to help find out.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Oasis or Sand Dune? Isolation of Psychedelic Compounds
January 20th 2025Magic mushrooms, once taboo, have recently experienced a renaissance. This new awakening is partially due to new findings that indicate the effects of psilocybin, and its dephosphorylated cousin psilocin may produce long lasting results for patients who might be struggling with anxiety, depression, alcohol and drug abuse, and post-traumatic stress disorder. Hamilton Company has developed a methodology for the isolation and identification of 5 common psychedelic compounds used in the potential treatment of disease. The PRP-1 HPLC column resin remains stable in the harsh alkaline conditions ideal for better separations.
