An innovative oral session called Liquid Chromatography: Stationary Phase Architecture chaired by Richard A. Henry from Supleco/Sigma Aldrich (Bellefonte, Pennsylvania) begins at 8:00 a.m. today in room 311C.
Session 430, Room 311C
An innovative oral session called Liquid Chromatography: Stationary Phase Architecture chaired by Richard A. Henry from Supleco/Sigma Aldrich (Bellefonte, Pennsylvania) begins at 8:00 a.m. today in Room 311C.
The discussion kicks off with an interesting presentation on the Characterization of Carbon-modified Silicas for Analytical Liquid Chromatography by Stephen R .Groskreutz from Gustavaus Adolphus College (St. Peter, Minnesota) followed by a talk on Using Solvent Particle Interactions to Predict Slurry Packing and Performance of 1.2 µm Superficially Porous Particles Packed in Capillary Columns for Liquid Chromatography by Laura Blue from the University of North Carolina (Chapel Hill, North Carolina).
A research project on the Performance Reproducibility of Chromatographic Columns Packed With Sub-3 µm Core-Shell Particles is described by Fabrice Gritti from the University of Tennessee-Knoxville (Knoxville, Tennessee). Richard A. Henry will then discuss the Equivalency of Selectivity Plots for Porous and Superficially Porous Particles.
A short interval in the proceedings is followed by a lecture by Chuan-Hsi Hung from Brigham Young University (Provo, Utah) on the Comparison of Efficiencies of Diamond-based Core-Shell Materials for HPLC Made with Different Sizes of Nano-diamonds and Core Carbon Particles.
1.2 µm Large Pore, Thin-shell Superficially Porous Particles and their Chromatographic Performance in Capillary LC Columns is described by James W, Treadway from the University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) followed by a talk on the Evaluation of 2 µm Nonporous Organolsilica Hybrid Particles for LC by Amber Moore from SUNY at Buffalo (Buffalo, New York).
The session closes with a presentation by Xiaddong Liu from Thermo Fisher Scientific (Sunnyvale. California) on High Performance Speciality Columns for Surfactant Analysis.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Metabolomics Analysis of Low Birth-Weight Infants Using UHPLC-MS/MS Following Lipid Emulsion
January 10th 2025A recent study aimed to directly compare the changes in serum metabolites among very low birth-rate (VLBW) infants following the administration of the soybean oil-based lipid emulsion and soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) lipid emulsion using untargeted metabolomics techniques.
Analyzing New Drug Modalities: An ISC 2024 Interview with Kelly Zhang
January 10th 2025At ISC 2024 in Liverpool, United Kingdom, LCGC International interviewed Kelly Zhang of Genentech about her work analyzing new drug modalities, such as mRNA, oligonucleotides, peptides, and cell and gene therapies.