Liquid Chromatography at the Extreme: Ultra-pressure and High Temperature

Pittcon 2008 got off to a great start here in New Orleans. The liquid chromatography sessions at the Ernest N. Morial Center were interesting and informative, such as the session entitled “Liquid Chromatography at the Extreme: Ultra-pressure and High Temperature.”

Jody Clark, Isabelle P. François, Frédéric Lynen, and Pat J. Sandra, opened the session with “High Efficiency Semi-Preparative Liquid Chromatography at Elevated Temperatures” discussing the changes that need to be made to current instrumentation to achieve increased sample capacity and the relevance of higher efficiency in semi-preparative HPLC.

That presentation was followed by “Effect of Temperature on Solvent-Strength Linearity in Reversed-Phase Liquid Chromatography” by Jason Coym, from the University of South Alabama, which offered insight into the interactions that lead to nonlinearity in solvent strength plots.

Next up was “Explore the Various Approaches to Evaluate the Stability and Lifetime of RP-HPLC Columns in High pH Con” by Lawrence Y. Loo, Ismail Rustamov, Tivadar Farkas, and Daniel Priegota focusing on the effects of different variables on the column lifetime in high pH conditions.

The last presentation before recess was by Roger K. Gilpin, Joseph G. Solch, Wanlong Zhou, and Christina S. Gilpin entitled “Theoretical Considerations When Carrying out Liquid Chromatography at Ultrahigh Pressure.”

After the recess, Richard Henry, Hillel Brandes, and Russel Gant got things restarted with their presentation, “Achieving Optimum UHPLC Column Performance by Measuring and Reducing Overall System Dispersion” followed by Jason Lieske’s discussion on,“ A Novel Ultra-High Pressure Liquid Chromatography (U-HPLC) Method for the Analysis of Vitamins in Cell Culture Medium.”

Next was David Thomas and Luisa Pereira’s presentation called, “Faster HPLC Separations at Elevated Temperature.” The final presentation was by Yansheng Liu and Milton L. Lee titled, “Evaluation of Diamond Particles as Stationary Phases for Liquid Chromatography.” Their talk focused on the potential for diamond particles to become more useful in LC.

It was a great session to kick-start what is sure to be an interesting and innovative week at Pittcon.