LCGC TV: Richard Henry on Optimizing UHPLC Methods

In this new video from LCGC TV, Attila Felinger from the University of Pécs, Hungary, defines the term “fast LC” and discusses how developments in fast LC technology have changed the field of bioanalysis.

In this video from LCGC TV, Mary J. Wirth of Purdue University explains the phenomenon of slip flow: what it is, how it can improve separations - particularly of proteins and monoclonal antibodies - and where it may take us in the future.

Comprehensive liquid chromatography (LC) is a multidimensional technique that has the potential to increase peak capacity resolution when separating complex mixtures, especially in food analysis. In this new video from LCGC TV, Luigi Mondello from the University of Messina, Italy, describes the fundamental principles of 2D LC, and explains the advantages over 1D LC.

Are mass spectrometers becoming too sensitive? Does performing ultrahigh-performance liquid chromatography (UHPLC) increase matrix effects? In this new video clip from LCGC TV, Frederic Lynen of Ghent University in Belgium discusses the challenges faced by analysts working in the field of bioanalysis and comments on potential solutions.

The Kinetic Plot method is a useful tool in LC method development to compare the performance of different LC columns with each other. In this new video from LCGC TV, Deirdre Cabooter from KU Leuven (Belgium) describes the range of techniques that it can be applied to and how it can help analysts in practice.

The Kinetic Plot method is a useful tool in LC method development to compare the performance of different LC columns with each other. In this new video from LCGC TV, Deirdre Cabooter from KU Leuven (Belgium) describes how to use the variable length method development strategy to develop successful UHPLC methods and how this approach can save time for the analyst.