LCGC TV: Richard Henry on Fully Porous vs. Superficially Porous Particles
Superficially porous particles for HPLC columns – often called "core–shell" particles have gotten a lot of attention in recent years because of their excellent performance. Yet so far, columns made with fully porous particles are still the most widely used. Will superficially porous particles eventually take over?
Mary J. Wirth on Slip Flow, Part I — How it Works
April 20th 2015In this video from LCGC TV, Mary J. Wirth of Purdue University explains the phenomenon of slip flow: what it is, how it can improve separations - particularly of proteins and monoclonal antibodies - and where it may take us in the future.
LCGC TV: Luigi Mondello on the Fundamentals of 2D LC
March 11th 2015Comprehensive liquid chromatography (LC) is a multidimensional technique that has the potential to increase peak capacity resolution when separating complex mixtures, especially in food analysis. In this new video from LCGC TV, Luigi Mondello from the University of Messina, Italy, describes the fundamental principles of 2D LC, and explains the advantages over 1D LC.
LCGC TV: Frederic Lynen on Performing UHPLC in Bioanalysis
October 8th 2014Are mass spectrometers becoming too sensitive? Does performing ultrahigh-performance liquid chromatography (UHPLC) increase matrix effects? In this new video clip from LCGC TV, Frederic Lynen of Ghent University in Belgium discusses the challenges faced by analysts working in the field of bioanalysis and comments on potential solutions.
LCGC TV: Dierdre Cabooter on Method Development in UHPLC
July 30th 2014The Kinetic Plot method is a useful tool in LC method development to compare the performance of different LC columns with each other. In this new video from LCGC TV, Deirdre Cabooter from KU Leuven (Belgium) describes the range of techniques that it can be applied to and how it can help analysts in practice.
LCGC TV: Using the Variable Length Method Development Strategy to Develop Successful UHPLC Methods
July 16th 2014The Kinetic Plot method is a useful tool in LC method development to compare the performance of different LC columns with each other. In this new video from LCGC TV, Deirdre Cabooter from KU Leuven (Belgium) describes how to use the variable length method development strategy to develop successful UHPLC methods and how this approach can save time for the analyst.
