LC–MS in Metabolomics
In this video, Robert T. Kennedy of the University of Michigan discusses the role of liquid chromatography–mass spectrometry (LC–MS) in the rapid development of metabolomics and the challenge of dealing with all the data. He then goes onto talk about the methods used in a recent study on glucose metabolism to analyse complex metabolic pathways and the challenges of using smaller samples.
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Navigating The Path To Modern Slalom Chromatography: An Interview with Fabrice Gritti
May 1st 2025Fabrice Gritti, consultant scientist at Waters Corporation, spoke to LCGC International about the history of slalom chromatography (SC) and why he decided that the technique was worth re-investigating. The potential benefits of SC, according to Gritti, include identifying RNA impurities when manufacturing mRNA therapeutics, and assisting in the development of new gene and cell therapies, and other biopharmaceutical applications.
New Method Explored for the Detection of CECs in Crops Irrigated with Contaminated Water
April 30th 2025This new study presents a validated QuEChERS–LC-MS/MS method for detecting eight persistent, mobile, and toxic substances in escarole, tomatoes, and tomato leaves irrigated with contaminated water.
Determining the Effects of ‘Quantitative Marinating’ on Crayfish Meat with HS-GC-IMS
April 30th 2025A novel method called quantitative marinating (QM) was developed to reduce industrial waste during the processing of crayfish meat, with the taste, flavor, and aroma of crayfish meat processed by various techniques investigated. Headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS) was used to determine volatile compounds of meat examined.
