HPLC 2015 Tuesday Afternoon Sessions
HPLC2015 Tuesday Afternoon Sessions
Session 19: Enantioselectivity
Room 1, Level 1
14:15 -Wolfgang Lindner: Chiral Ion Exchanger for Stereoselective Resolutions: Peculiarities, Operational Flexibility, Applicability Spectrum
14:45 - C.J. Venkatramani: Design and Applications of 2D LCxSFC in Pharmaceutical Analysis
15:05 -Kenji Hamase: Chiral Amino Acid Targeted Metabolomics for Clinical Diagnosis Using Enantioselective Two-dimensional HPLC Tandem-mass Spectrometry
15:25 - Alessia Ciogli: On the use of the Sub-2-µm Whelk-O 1 stationary phase in enantioselective ultra-high performance SFC
Session 20: Proteomics
Room 2, Level 0
14:15 -Barry Karger: Advanced Glycoprotein Structural Characterization Using Top-Down High-Resolution CZE–MS
14:45 -Ying Zhang: Improving Peptide Selectivity by Using LC-SWATH/MS Acquisition Method with Variable Isolation Window Widths: An Additional Separation Step at Mass Level
15:05 - Alexey Makarov: New Approach of Using Pressure in Reversed-Phase Liquid Chromatography to Study Protein Conformational Changes by Differential Deuterium Exchange
Session 21: Food Science
Room 3 + 4, Level 0
14:15 - Luigi Mondello: Elucidation of the Carotenoid Composition in Food using One- and Two-Dimensional Chromatography Coupled to Photodiode Array and Mass Spectrometry Detection
14:45 -Helmut K. Mayer: UHPLC Analysis of Biogenic Amines in Different Cheese Varieties Retailed in Austria
15:05 - Yoshiyuki Watabe: Comprehensive Two-Dimensional HPLC Analysis and Informative Data Processing for Pharmaceuticals and Lipids
15:25 - Stephen Pickrahn: Application of Preparative 2D-LC in Natural Product Taste Research (2D-SENSOMICS) Utilizing Innovative Scale-Ip Approaches
Tutorial 05: Modern SFC
Room 5 + 6, Level 3
14:45–15:30: Abhijit Tarafdera & Caroline West: Modern SFC: What Analytical Chemists Should Know About It?
Session 22: Selectivity
Room 1, Level 1
16:45 -Koji Otsuka: Simplified High Performance CE Separations of Biomolecules
17:00 - Doo Soo Chung: Micro-Headspace In-Tube Microextraction coupled with Capillary Electrophoresis
17:35 - José Manuel Herrero-Martínez: Monolithic Columns with a High Coverage of Silver Nanoparticles for Nano-LC Separation of Small Molecules and Proteins
17:55 - Bertyl Andri: Investigation and Modelling of the Retention Mechanisms in Supercritical Fluid Chromatography with the Help of Chemometric Tools
Session 23: Proteins
Room 2, Level 0
16:45 - David Hage: Affinity Microcolumns as Tools for Examining the Binding and Rates of Drug-Protein Interactions in Solution
17:15 -Zhen Liu: New boronate affinity stationary phases for affinity separation and enrichment
17:35 -Lars Büter: Differential Labeling of Cysteine Residues in Proteins based on Electrochemically Generated Reactive Species
17:55 -Staffan Nilsson: SAW-MALDI MS: Open Chip for Biomolecule Sample Handling; Impact of Ionic Liquids on Hormone Secretion from Langerhans Islets
Session 24: Metabolomics
Room 3 + 4, Level 0
16:45 - Thomas Hankemeier: Remaining Challenges in Metabolomics, and Strategies to Address Them
17:15 -Marc J.F. Suter: Multimode Gradient Separation for Metabolomics and Environmental Monitoring
17:35 -Michael Witting: Evaluation of Different Algorithms in QSRR to Filter False Positive Annotations in LC–MS-Based Metabolomics
17:55 - Georgios Theodoridis: Metabolomics for Biomarker Discovery in Perinatal Health
Tutorial 06
Room 5 + 6, Level 3
17:15 – 18:00 -Fabrice Gritti: Mass Transfer Processes Inside Modern Chromatographic Columns
Presenting GC Data Comparisons to Laypersons to Understand Potential Courtroom Implications
January 6th 2025In forensic science, scientific testimony is routinely presented in court to juries who may have limited or no scientific background, putting law enforcement and defense personnel in the position of having to make rapid decisions in short timeframes based on findings of which they are not specialists. Katelynn Perrault Uptmor, Assistant Professor of Chemistry at William & Mary (Williamsburg, Virginia) believes that the introduction of new technologies into the framework of routine forensic analysis must therefore bridge the gap between introduction of new and novel analytical science and the communication of that science to a court of law, and that analytical chemistry research must be mindful of the need to fill this gap in promoting new technologies.
Detailed Glycosylation Analysis of Therapeutic Enzymes Utilizing Comprehensive 2D-LC–MS
January 3rd 2025In this article, the use of comprehensive two-dimensional liquid chromatography (LC×LC) coupled to mass spectrometry (MS) for characterizing glycosylation of therapeutic enzymes is presented.
Advancing Gene Therapy: Enzyme Selection for Effective RNA Oligonucleotide Mapping
New gene therapy modalities, such as CRISPR guide RNA (single guide ribonucleic acid [sgRNA]) and messenger RNA (mRNA), continue to make progress in both primate and first-in-human trials. As this progress builds, the industry remains accountable for characterizing these molecules to meet the requirements of regulatory authorities.
