HPLC 2015 Monday Morning Sessions
HPLC 2015 Monday Morning Sessions
Plenary Lecture: 08.30 - Jack Henion: Past, Present, and Future of LC–MS
Room 1, Level 1
Session 01: Column Design, Stationary Phase
Room 1, Level 1
09:20 -Mary J. Wirth (ChromSoc Award – Jubilee Medal): Submicrometer Particles in Protein Chromatography
09:50 -Sander Deridder: Transverse Dispersion in Porous Media
10:10 - Tivadar Farkas: Has Core–Shell Particle Technology Reached Maturity?
Session 02: Mass Spectrometry
Room 2, Level 0
09:20 - Renato Zenobi: Design and Applications of a Robust and Compact Active Capillary Plasma Ionization Source for Detection by Mass Spectrometry
09:50 - Markus Himmelsbach: Mass Spectrometry of Sample Spots Directly from TLC Plate Tips. A Powerful Tool for Rapid and Easy Identification and Quantification
10:10 -Sangwon Cha: Extractive Ambient Ionization Mass Spectrometry for Direct Raw Material Analysis
Session 03: Sample Preparation
Room 3 + 4, Level 0
09:20 - Janusz Pawliszyn: Application of SPME in High Throughput and In-Vivo Drug Quantification
09:50 -Paul Haddad: Purely Aqueous Electrophoretic Preconcentration of Charged Analytes Using Glass Micropipettes and Hydrogel
10:10 - Astrid Gjelstad: Parallel Artificial Liquid Membrane Extraction – A New Way to Perform Selective Sample Preparation from Biological Matrices
Tutorial 01
Room 5 + 6, Level 3
09:50 - Stephan Lamotte: Testing HPLC and UHPLC Instruments – How to Identify the Right Instrument for Your Application
Session 04: Column Design, Stationary Phase
Room 1, Level 1
11:20 - Massimo Morbidelli: Continuous Chromatography for Proteins Purification
11:50 -James Heaton: Some Factors that can lead to Poor Peak Shape in Hydrophilic Interaction Chromatography, and Possibilities for their Remediation
12:10 - Mike De Vrieze: Assessment of a Novel Phosphocholine Based Micellar LC Approach and of Immobilized Artificial Membrane Phases for Improved Prediction of In Vivo Drug Behaviour
Session 05: LC–MS Ion Mobility
Room 2, Level 0
11:20 -Colin Creaser: Combining Field Asymmetric Waveform Ion Mobility Spectrometry with Liquid Chromatography–Mass Spectrometry for the Analysis of Small Molecules and Metabolites
11:50 -Bandar Alghanem: Sensitivity and Selectivity Evaluation of Peptides Quantification Using Ion Mobility Spectrometry and Cubed Selected Reaction Monitoring
12:10 - Martin Zühlke: ESI Ion Mobility Spectrometry as Detection Method in HPLC
Session 06: Sample Preparation
Room 3 + 4, Level 0
11:20 -Valérie Pichon: Real Potential of Molecularly Imprinted Polymers for the Selective Extraction of Target Compounds from Complex Samples
11:50 - Stig Pedersen-Bjergaard: Microextraction Across Artificial Liquid Membranes in 96-Well Format – A New Approach to Sample Preparation for Liquid Chromatography
12:10 - Gongke Li: Magnetic Derived Perhydroxy-cucurbit[8]uril Nanoparticles Solid-Phase Extraction for Ultrasensitive Determination of Cytokinins in Plant Samples by UHPLC–MS–MS
Presenting GC Data Comparisons to Laypersons to Understand Potential Courtroom Implications
January 6th 2025In forensic science, scientific testimony is routinely presented in court to juries who may have limited or no scientific background, putting law enforcement and defense personnel in the position of having to make rapid decisions in short timeframes based on findings of which they are not specialists. Katelynn Perrault Uptmor, Assistant Professor of Chemistry at William & Mary (Williamsburg, Virginia) believes that the introduction of new technologies into the framework of routine forensic analysis must therefore bridge the gap between introduction of new and novel analytical science and the communication of that science to a court of law, and that analytical chemistry research must be mindful of the need to fill this gap in promoting new technologies.
Detailed Glycosylation Analysis of Therapeutic Enzymes Utilizing Comprehensive 2D-LC–MS
January 3rd 2025In this article, the use of comprehensive two-dimensional liquid chromatography (LC×LC) coupled to mass spectrometry (MS) for characterizing glycosylation of therapeutic enzymes is presented.
Advancing Gene Therapy: Enzyme Selection for Effective RNA Oligonucleotide Mapping
New gene therapy modalities, such as CRISPR guide RNA (single guide ribonucleic acid [sgRNA]) and messenger RNA (mRNA), continue to make progress in both primate and first-in-human trials. As this progress builds, the industry remains accountable for characterizing these molecules to meet the requirements of regulatory authorities.
