HPLC 2015 Monday Afternoon Sessions
HPLC 2015 Monday Afternoon Sessions
Session 07: Georges Guiochon
Room 1, Level 1
14:15 - Attila Felinger: Mass Transfer in HPLC – A Molecular Approach
14:45 - Alberto Cavazzini: Considerations on the Kinetic Performance of Columns Packed with New 1.9 μm Fully Porous Particles of Narrow Particle Size Distribution
15:15 - Torgny Fornstedt: Visualization and Explaining Serious Deformations in Supercritical Fluid Chromatography Due to the Very Injection Principle
Session 08: Mass Spectrometry
Room 2, Level 0
14:15 - Bernd Bodenmiller: Highly Multiplexed Tissue Imaging with Subcellular Resolution by CyTOF Mass Cytometry
14:30 - Christian Lanshoeft: High-Throughput Quantitative Analysis of Small Molecules in Clinical Samples Using Laser Diode Thermal Desorption Tandem Mass Spectrometry (LDTD–MS–MS)
14:50 - Robert Plumb: Development of a High Throughput Integrated, Multi-Disciplinary “Omics” Platform to Support Basic Research into Disease Understanding and Patient Stratification
15:10 - Thomas Letzel: RPLC–HILIC vs. SFC – Novel Screening Techniques with Strongly Extended Polarity
Session 09: Microfluidics
Room 3 + 4, Level 0
14:15 - Brendon Seale: Front-End Sample Processing for Separations and Mass Spectrometry Using Digital Microfluidics
14:30 - Will Black: Utilizing Microchip Capillary Electrophoresis-Electrospray Ionization for Hydrogen Deuterium Exchange Mass Spectrometry
14:50 - Bifeng Liu: Single Cell Omic Analysis by Micofluidic-Coupled Electrophoresis
15:10 - Margaryta Ianovska: Development of Small-Volume, Microfluidic Chaotic Mixers for Application in Two-Dimensional Liquid Chromatography
Tutorial 02
Room 5 + 6, Level 3
14:45 - Frank Steiner and Thorsten Teutenberg: The Role of Temperature in HPLC from Speed Increase and Selectivity Tuning to Greener Chromatography and Special Detection Far Beyond 100 °C
Session 10: Georges Guiochon
Room 1, Level 1
16:45 - Fabrice Gritti: The Relative Importance of the Adsorption and Partitioning Mechanisms in Hydrophilic Interaction Liquid Chromatography
17:00 - Kanji Miyabe: Chromatographic Capillary Electrophoresis (CCE): A Strategy for Analyzing Equilibrium and Kinetic Characteristics of Intermolecular Interaction
17:20 - Michel Martin: The Impact of Viscous Fingering in Preparative Liquid Chromatography
17:40 - Abhijit Tarafder: Fundamental Difference in Method-Transfer Between HPLC and SFC and its Solution
Session 11: Hyphenation
Room 2, Level 0
16:45 - Marja-Liisa Riekola: Potential of Tailor-Made Materials for Air Sampling and for Challenging Biomolecule Isolation by Exploiting Miniaturized Extraction Systems
17:00 - Jorg Roscher: Photochemical Transformation of Contaminants in the Aqueous Environment – Identification of Occurring Products by means of LC-MS
17:20 - Rui Zhao: Develop On-line SCF–SPE–LC–FTICR MS Platform for Sensitive Analysis of Soil Organic Materials (SOM)
17:40 - Meritxell Navarro Reig: Untargeted HPLC–HRMS Metabonomics for Studying the Effects of Cadmium and Copper Exposure in Japanese rice (Oryza sativa japonica)
Session 12: Supercritical Fluid Chromatography
Room 3 + 4, Level 0
16:45 - Frederic Lynen: Development of Hydrogenated Synthetic Diamond Particles and of Novel Cyclic Organosilane Based Materials for Ultra-High Temperature HPLC and SFC
17:00 - Tomas Leek: Determining the Unknown Knowns in Fragment Libraries by SFC–MS
17:20 - Lucie Novakova: Evaluation of Enantioselectivity Differences of Polysaccharide Stationary Phases in SFC Chiral Separations
17:40 - Robert Buco: Fully Automated On-line Supercritical Fluid Extraction and SFC–MS
Tutorial 03
Room 5 + 6
17:15 - Gabriel Vivó-Truyols: Data Analysis in Chromatography: The Old Battle of Bayesian vs. Frequentist Revisited
Presenting GC Data Comparisons to Laypersons to Understand Potential Courtroom Implications
January 6th 2025In forensic science, scientific testimony is routinely presented in court to juries who may have limited or no scientific background, putting law enforcement and defense personnel in the position of having to make rapid decisions in short timeframes based on findings of which they are not specialists. Katelynn Perrault Uptmor, Assistant Professor of Chemistry at William & Mary (Williamsburg, Virginia) believes that the introduction of new technologies into the framework of routine forensic analysis must therefore bridge the gap between introduction of new and novel analytical science and the communication of that science to a court of law, and that analytical chemistry research must be mindful of the need to fill this gap in promoting new technologies.
Detailed Glycosylation Analysis of Therapeutic Enzymes Utilizing Comprehensive 2D-LC–MS
January 3rd 2025In this article, the use of comprehensive two-dimensional liquid chromatography (LC×LC) coupled to mass spectrometry (MS) for characterizing glycosylation of therapeutic enzymes is presented.
Advancing Gene Therapy: Enzyme Selection for Effective RNA Oligonucleotide Mapping
New gene therapy modalities, such as CRISPR guide RNA (single guide ribonucleic acid [sgRNA]) and messenger RNA (mRNA), continue to make progress in both primate and first-in-human trials. As this progress builds, the industry remains accountable for characterizing these molecules to meet the requirements of regulatory authorities.
