DryLab 4 is the next generation UHPLC modeling software. With its comprehensive resolution and robustness mapping abilities, DryLab 4 offers an intuitive and visual solution for method development, optimization, trouble-shooting, robustness testing, and training.
DryLab 4 is the next generation (U)HPLC modeling software. With its comprehensive resolution and robustness mapping abilities, DryLab 4 offers an intuitive and visual software solution for method development, optimization, trouble-shooting, robustness testing, and training. DryLab 4’s 3D modeling capabilities and its multifactorial evaluation of flow rate, column dimensions, instrument parameters, and eluent composition in gradient and isocratic work, provide users with the tools to easily conform to Quality by Design standards. A further robustness evaluation helps users to find the robustness thresholds of their method, and determines which parameters exert the most influence on the critical resolution.
Our latest DryLab 4 feature, the Knowledge Management reporting tool, generates a complete method report, including the Design of Experiments, the 3D model, the robustness calculations, the comparison in retention times between the experimental and predicted outcomes, and all justifications for the method choices. This software tool encourages users to follows a QbD approach to method development, and helps ensure that the completed method conforms to these standards.
Website:
www.molnar-institute.com
Characterizing Plant Polysaccharides Using Size-Exclusion Chromatography
April 4th 2025With green chemistry becoming more standardized, Leena Pitkänen of Aalto University analyzed how useful size-exclusion chromatography (SEC) and asymmetric flow field-flow fractionation (AF4) could be in characterizing plant polysaccharides.
Investigating the Protective Effects of Frankincense Oil on Wound Healing with GC–MS
April 2nd 2025Frankincense essential oil is known for its anti-inflammatory, antioxidant, and therapeutic properties. A recent study investigated the protective effects of the oil in an excision wound model in rats, focusing on oxidative stress reduction, inflammatory cytokine modulation, and caspase-3 regulation; chemical composition of the oil was analyzed using gas chromatography–mass spectrometry (GC–MS).