Faster, Simpler Method Scaling Across Particle Sizes Using the Waters Columns Calculator Compared to Manual Calculation Workflow
When scaling an established analytical method across columns packed with different particle sizes and different column configurations (internal diameters and lengths), the amount of time that is required outside of the lab to produce the equivalent method conditions is considerable. When dealing with a gradient method, the calculations required include determining the new flow rate, gradient times, and injection volume. An analyst can perform these calculations manually using the appropriate equations or tools like the Waters Columns Calculator. This app note examines two scaling workflows by first performing a theoretical scale-down experiment manually using the appropriate method scaling equations, and then repeating the experiment using the scaled-down conditions generated by the Waters Columns Calculator. Strong agreement between manual calculations and the results using the Waters Columns Calculator validate the Waters Column Calculator for its use in scaling methods effectively, with a significant improvement in time savings and a reduction in potential calculation errors and/or uncertainties.
Infographic: Be confidently audit ready, at any time and reduce failures in pharma QC testing
November 20th 2024Discover how you can simplify the audit preparation process with data integrity dashboards that provide transparency to key actions, and seamlessly track long-term trends and patterns, helping to prevent system suitability failures before they occur with waters_connect Data Intelligence software.
6PPD-Quinone Reference Materials
November 19th 2024Ensure environmental and consumer health with our standards for 6PPD-quinone testing. 6PPD-quinone has been detected in the environment and has shown toxicity to aquatic life. Chiron, by Zeptometrix® offers reference standards suitable for Draft EPA Method 1634.
Current and Future Advancements in PFAS Research
November 19th 2024This white paper explores the health risks, environmental impacts, and detection technologies associated with PFAS, along with the latest advancements in PFAS research. It also provides an overview of the regulatory landscape and emphasizes the crucial role of companies like ZeptoMetrix® in supplying PFAS reference materials, which are essential for ensuring the accuracy of testing. Lastly, the paper outlines key areas for future PFAS research.
Microplastics Reference Materials
November 19th 2024The World’s First Microplastics Reference Materials. Our scientists have focused on these emerging global threats, and are excited to share Chiron MicroPrefs®, the first commercial microplastic reference material. The MicroPref® portfolio is designed to detect the six most abundant plastics in the environment and is available in a novel, easy-to-use tablet formulation. Be among the first labs to join in the fight against microplastic pollution by exploring the NEW line of Chiron MicroPrefs® microplastic standards.
