The ACQUITY UPC2 System utilizes a powerful new analytical technique, convergence chromatography, giving you reliability, robustness, selectivity, and throughput never before thought possible. With UPC2 Technology, you?ll change the way you address chromatographic challenges.
An essential separations technique for your laboratory
UltraPerformance Convergence Chromatography™ (UPC2®) is a broad-based, complementary analytical platform that is taking its place alongside of LC and GC as one of the three essential separation technologies for modern laboratory analysis.
Orthogonality you can rely on
The ACQUITY UPC2™ System should be your go-to technology platform that can routinely provide reliable orthogonal data. Impurity, degradation peaks, or structurally similar compounds may often be overlooked during analysis. Orthogonal methods that provide different elution orders of peaks are needed to ensure full characterization. Adopt UPC2 into your laboratory, and you’ll experience a faster, more reliable route to orthogonal separations to LC and GC.
Simplified workflow
Because UPC2 can receive samples in organic solvents, it significantly simplifies the requirements for sample preparation, while maintaining all the advantages of RPLC.
With the ACQUITY UPC2 System, the impact on workflow starts with the time saved in sample preparation; add in the time saved in analysis and data interpretation, and you have a complete measurement for a faster route to answers.
The ACQUITY UPC2 System utilizes a powerful new analytical technique, convergence chromatography, giving you reliability, robustness, selectivity, and throughput never before thought possible. With UPC2 Technology, you’ll change the way you address chromatographic challenges.
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Polysorbate Quantification and Degradation Analysis via LC and Charged Aerosol Detection
April 9th 2025Scientists from ThermoFisher Scientific published a review article in the Journal of Chromatography A that provided an overview of HPLC analysis using charged aerosol detection can help with polysorbate quantification.
Analyzing Vitamin K1 Levels in Vegetables Eaten by Warfarin Patients Using HPLC UV–vis
April 9th 2025Research conducted by the Universitas Padjadjaran (Sumedang, Indonesia) focused on the measurement of vitamin K1 in various vegetables (specifically lettuce, cabbage, napa cabbage, and spinach) that were ingested by patients using warfarin. High performance liquid chromatography (HPLC) equipped with an ultraviolet detector set at 245 nm was used as the analytical technique.
Removing Double-Stranded RNA Impurities Using Chromatography
April 8th 2025Researchers from Agency for Science, Technology and Research in Singapore recently published a review article exploring how chromatography can be used to remove double-stranded RNA impurities during mRNA therapeutics production.