Erin Baker, an associate professor of chemistry at North Carolina State University, is the 2022 recipient of the ASMS Biemann Medal. Baker will receive the medal at the 2022 ASMS Conference in Minneapolis, Minnesota, which takes place June 5–9. She will receive the medal and deliver a plenary lecture on June 7 at 4:45 pm CST.
The Biemann Medal is awarded to an individual early in his or her career in recognition of significant achievement in basic or applied mass spectrometry. The Biemann Medal was established by contributions from students, postdoctoral associates, and friends to honor Professor Klaus Biemann. The medal is conferred at the ASMS Annual Conference with the presentation of a $5,000 cash award, the Biemann Medal, and the award lecture.
Baker is receiving the award for her significant contributions in the development and application of ion mobility spectrometry–mass spectrometry (IMS–MS) technologies. Examples of Baker’s innovative scientific contributions include the development of new IMS techniques and methods and significant contributions to the improvement of drift tube IMS (DTIMS) platforms, coupling this improved IMS–MS platform with solid-phase extraction (SPE) and liquid chromatography (LC) separations to enable high-throughput IMS measurements with enhanced sensitivity for metabolomics, lipidomics, proteomics, and exposomics applications. She has also created of one of the first collision cross section (CCS) databases for more than 500 metabolites and xenobiotics to enable large-scale metabolomics and exposomic studies by IMS technology. In addition, she has developed a cheminformatic toolbox called Structural-based Connectivity and Omic Phenotype Evaluations (SCOPE), to enable the assessment and visualization of lipidomic associations in environmental and clinical studies.
Baker also has contributed to the MS community through her key role in the establishment of the new group “Females in Mass Spectrometry (FeMS)” whose initial activities coincided with the onset of the coronavirus pandemic. During this situation that isolated individuals from their communities, FeMS has built an extensive worldwide network (also including males transgender, and nonbinary participants) that provides frequent virtual opportunities for education, collaboration, and mentorship.
Identifying Antioxidative Properties in Berries with UHPLC-MS
Published: November 27th 2024 | Updated: November 27th 2024A recent study identified and quantified anthocyanin (which are known for their antioxidative properties and potential effectiveness against depression) in blueberries, blackberries, black mulberries, and cranberries using ultra high-pressure liquid chromatography (UHPLC) followed by in vivo evaluation of their antidepressant-like activities.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
Innovative cryogen-free ambient air monitoring of trace-level air toxics at high humidity
November 27th 2024This application note presents an advanced analytical system for the sensitive detection of trace-level air toxics in humid ambient air samples, in accordance with US EPA Method TO-15A. The cryogen-free preconcentration and thermal desorption approach, coupled to GC-MS, delivers exceptional chromatographic performance even for highly volatile and polar compounds. The system meets the stringent detection limit requirements of the latest air monitoring regulations, with method detection limits as low as 0.7 pptv. This innovative analytical solution provides a robust, cost-effective platform for the reliable quantification of hazardous air pollutants, enabling compliance with regulatory standards.
Continuous, cryogen-free on-line monitoring of PAMS in ambient air using hydrogen carrier gas
November 27th 2024This application note explores an efficient, helium-free method for continuous monitoring of ozone precursors in ambient air, aligned with EPA PAMS requirements. By using hydrogen as the carrier gas, this approach achieves faster run times, stable retention times, and effective separation of volatile organic compounds. A case study from New York City highlights the system's performance in urban air quality monitoring, capturing shifts in pollutant levels during periods of reduced traffic. With remote operability and cryogen-free functionality, this method offers a reliable and sustainable solution for real-time air quality analysis in both urban and remote environments.