Differentiating oxidative metabolite isomers of the molecular glue, mezigdomide, using electron-activated dissociation (EAD)

The Axcend FocusArray is the ideal choice for your challenging liquid chromatography requirements. The only diode array detectr for capillary HPLC offers a full three orders of magnitude linearity needed to identify trace elements in the presence of your target analytes.

The Focus LC high-performance liquid chromatography (HPLC) system is small enough to be easily placed near the sample source and powerful enough to be used in any state-of-the-art laboratory. It’s optimized for low solvent consumption, waste reduction, and energy conservation, and delivers the performance and reliability you need for the highest confidence in your daily results.

InFocus enables real-time in-line sampling, ensuring process integrity throughout the workflow, including inside a hood or next to a reaction vessel. Scientific breakthroughs and process optimizations require fast, accurate, and reliable data. As a Process Analytical Technology (PAT) tool, the InFocus enables real-time, in-line, on-line, and at-line analysis, allowing scientists and engineers to detect inefficiencies, optimize reactions, and improve product quality without delays.

AutoFocus autosampler allows automated and unattended introduction of multiple standards and samples to the Axcend Focus LC for separation and analysis. The automated sampling system streamlines precision sample injection, improving efficiency and throughput. Designed for effortless operation and maintenance, AutoFocus offers excellent performance, making it the ideal autosampler for unattended analyses.

A full-stack capillary HPLC system, such as the one recently launched by Axcend, integrates several innovative features that set it apart from traditional HPLC systems. This compact system includes a 40-vial/96-well plate autosampler, an in-line process analytical technology (PAT) monitoring system, and a full-spectrum diode array detector (DAD). These components work together to enable real-time data analysis at the point of sampling, significantly enhancing productivity and precision. One of the most remarkable aspects of this system is its small footprint, which optimizes valuable lab and production space while reducing costs and environmental impact (the base measures 13" X 9"). The low-flow design minimizes solvent consumption and hazardous waste, aligning with sustainable laboratory practices. Additionally, the system's ability to perform HPLC anywhere—whether inside a hood or next to a reaction vessel—provides unparalleled flexibility for scientists.