Award Symposium: The LCGC Lifetime Achievement and Emerging Leader Awards
This afternoon, the winners of the LCGC Awards will be honored in an oral symposium at Pittcon. Milton L. Lee of Brigham Young University will receive the 2016 LCGC Lifetime Achievement Award at 1:30, and Debby Mangelings of the Free University of Brussels (Vrie Universiteit Brussel), will receive the 2016 LCGC Emerging Leader Award at 3:45 pm, just after the break. The symposium will be held in room B314.
This afternoon, the winners of the LCGC Awards will be honored in an oral symposium at Pittcon. Milton L. Lee of Brigham Young University will receive the 2016 LCGC Lifetime Achievement Award at 1:30, and Debby Mangelings of the Free University of Brussels (Vrie Universiteit Brussel), will receive the 2016 LCGC Emerging Leader Award at 3:45 pm, just after the break. The symposium will be held in room B314. Following the presentation of the Lifetime Achievement Award, Lee will give a talk on columns in small-scale chromatography. Pat Sandra of the Research Institute for Chromatography will then discuss recent chromatographic and mass spectrometric developments applied to the characterization of recombinant proteins, monoclonal antibodies, and antibody-drug conjugates. Rounding out the first part of the program, Milos Novotny of Indiana University will give a presentation entitled, “Analytical Glycoscience: Quo Vadis?” After receiving the Emerging Leader Award, Mangelings will discuss generic chiral separation strategies for pharmaceutical compounds using chromatographic and electrophoretic techniques. Bezhan Chankvetadze of Tbilisi State University will then discuss recent trends in HPLC separation of enantiomers. Read about Lee and Mangelings in the article in our February issue.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
