During ASMS 2024, which will take place June 2–6, 2024 in Anaheim, California, many scientists are set to present research on the latest advances in mass spectrometry. Recently, LCGC International sat down with Nick Riley of the University of Washington to discuss his presentation, "Comparative Analysis of Glycoproteomic Software Tools Using a Tailored Glycan Database."
Nicholas M. Riley received his B.S. in chemistry and psychology from the University of South Carolina in 2012, with Honors from the South Carolina Honors College. His undergraduate research in forensic analytical chemistry with Stephen Morgan first introduced him to mass spectrometers. He quickly became fascinated with these instruments, which led him to his Ph.D. work in mass spectrometry (MS) instrumentation and proteomics with Joshua Coon at the University of Wisconsin–Madison. In the Coon group, he developed MS technology for gas-phase ion-ion reactions, with an emphasis on a tandem MS method called electron transfer dissociation (ETD) that he applied in analyses of peptides, proteins, and post-translational modifications (1).
In this interview, Riley answers the following questions:
(1) Nicholas M. Riley. University of Washington 2024. https://chem.washington.edu/people/nicholas-m-riley (accessed 2024-5-24)
Pharmaceutical excipients, such as polyethylene glycol-based polymers, must be tested for the presence of ethylene oxide (EtO) and 1,4-dioxane as part of a safety assessment, according to USP Chapter <228>.
Investigating Synthetic Cathinone Positional Isomers using LC–EAD-MS
November 7th 2024Peng Che fom Vrije Universiteit Amsterdam in the Netherlands discusses the benefits of hyphenating liquid chromatography (LC) with electron activated dissociation mass spectrometry (EAD-MS) to analyze cathinone positional isomers.