Applying Analytical Method Greenness Scoring to the USP Monograph of Naproxen; Improving the Sustainability of Validated Methods by Modernizing to Newer Technology
In this application note the USP monograph method for naproxen sodium tablets was modernized and Analytical Method Greenness Scoring (AMGS) values were assigned to each system used. The use of newer technology including sub-2 µm columns provides not only improvements to throughput and solvent usage but also drastically improved AMGS values.
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Pick Your Poison. Isolation of Paclitaxel (Mar 2025)
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The diterpenoid, paclitaxel, which was identified as a potent chemotherapy agent for breast and ovarian cancer originates from the Pacific Yew tree. The isolation of paclitaxel from its major impurities is shown with the use of Hamilton’s PRP-1 (5 µm) HPLC column.
