Analytical technology solutions showcased
Waters showcased the breadth and depth of applications for liquid chromatography and mass spectrometry at last month?s American Association of Clinical Chemistry annual meeting and Clinical Lab Expo.
Waters showcased the breadth and depth of applications for liquid chromatography and mass spectrometry at last month’s American Association of Clinical Chemistry annual meeting and Clinical Lab Expo.
The company reports that its portfolio of solutions for the clinical laboratory combines the power of separations science, tandem mass spectrometry, specialized chemistries, software and support services in ways designed to optimize laboratory processes.
This year’s conference features more than 27 presentations on applications for LC–MS including a poster being presented by Waters’ scientists in collaboration with clinical scientists at Newcastle Hospital, UK. The poster was titled “Analysis of metanephrines in plasma by automated solid-phase extraction with ACQUITY Amide hydrophilic interaction liquid chromatography tandem mass spectrometry”.
For more information visit www.waters.com
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Metabolomics Analysis of Low Birth-Weight Infants Using UHPLC-MS/MS Following Lipid Emulsion
January 10th 2025A recent study aimed to directly compare the changes in serum metabolites among very low birth-rate (VLBW) infants following the administration of the soybean oil-based lipid emulsion and soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) lipid emulsion using untargeted metabolomics techniques.
PFAS Analysis in Practice: A RAFA 2024 Interview with Stefan van Leuwen
January 10th 2025At the Recent Advances in Food Analysis (RAFA) conference in 2024, LCGC International sat down with Stefan van Leuwen of Wageningen Food Safety Research to discuss his research, which addresses emerging challenges in circular food production, focusing on the risks posed by pollutants when waste and by-products are repurposed in food systems.
