Analytical-Scale Prep, Semi-Prep, Process Scale Preparative Chromatography: To Infinity and Beyond!

Register Free: https://www.chromatographyonline.com/lcgc_w/prep

Event Overview:

Are you planning to turn your analytical HPLC method into a purification method? Are you converting your analytical-scale purification method to semi-prep or production scale? No matter what scale of preparative chromatography you are trying to tackle, knowing where to start and how to scale up are essential to your success. Learn how to set appropriate purification goals for purity, yield, and throughput and what type of equipment will best fit your application. This webinar will discuss:

• Setting objectives for preparative HPLC Separations
• How to get started with preparative HPLC
• Analytical-scale prep, semi-prep, prep? What is the right fit for my application?
• What is the difference in efficiency between a single injection vs. batch processing to separate large quantities?
• What are the calculations for scale-up from analytical to prep and is there a shortcut that works?
• How can I pack my own columns? What is the benefit of self-packing columns?

Key Learning Objectives:

• Learn how to scale up from analytical HPLC methods to larger scale preparative HPLC.
• Understand purification terminology and how to set goals regarding purity vs. yield vs. throughput
• Learn to use a scale up calculator to enable choices of column dimension and/or appropriate equipment configuration

Who Should Attend:

• Lab Managers, Research Scientists, Lab Technicians

Speakers

Lori Sandford
Application Scientist
Agilent

Lori Sandford is an HPLC Applications Scientist with Agilent Technologies, Inc. in Wood Dale, IL. Lori has been working at Agilent Technologies supporting HPLC instrumentation since 2010. Prior to Agilent, she was the Global Technology Manager for Prep and Process Chromatography at W. R. Grace/Alltech. Her career started at G.D. Searle/Pfizer in 1998 as a chromatography specialist in the Prep and Process Chromatography group supporting both medicinal and process separations. When she isn’t tinkering with an HPLC instrument in the lab, you’ll find her watching her kids play ice hockey and dabbling on the ice herself. A favorite new hobby is nurturing some sourdough starter and learning to bake bread.

Gina Black
Application Scientist
Agilent

Gina Black joined Agilent over 3 years ago and brought with her a wealth of experience in the pharmaceutical industry.She began her career at Merck as a synthetic chemist and became a subject matter expert in preparative HPLC, eventually joining the Separations Center of Excellence (COE), supporting both discovery and process development efforts.After twenty-two years at Merck, Gina moved to Bristol-Myers Squibb where she served as a site lead for their Single Compound Purification group, using a highly automated workflow to analyze, purify, and deliver final products for biological testing.Gina then moved back into large scale separations and enabling technologies supporting Chemical Development at BMS.Over the years, Gina has developed an extensive background in both reversed-phase and normal-phase HPLC, SFC, and IEX methodologies.

Register Free: https://www.chromatographyonline.com/lcgc_w/prep