Analysis & Purification of Oligonucleotides: Method Development Optimization from Characterization to Purification
Webinar Dates/Times: Wednesday, December 14th, 2022 at 10am EST|3pm GMT Wednesday, December 14th, 2022 at 2pm EST|11am PST Thursday, December 15th, 2022 at 12pm JST|11am CST
Therapeutic Oligonucleotides (oligos) have emerged as an area of particular interest and promise in biopharmaceutical research because of their potential to treat a wide range of diseases. In this webinar we will discuss some of the unique chromatographic challenges that oligonucleotides present and offer method development guidelines and optimizations for analytical characterization through scale up to preparative purification.
Register Free: https://globalmeet.webcasts.com/starthere.jsp?ei=1583731&tp_key=528be5846d
Event Overview:
Therapeutic oligonucleotides (oligos) have emerged as an area of particular interest and promise in biopharmaceutical research because of their potential to treat a wide range of diseases. These oligos can range in size, sequence complexity, and overall modifications. As a result, the analysis and purification of oligonucleotides by liquid chromatography is complex.
In this webinar, we will discuss some of the unique chromatographic challenges that oligonucleotides present and offer method development guidelines and optimizations for analytical characterization through scale up to preparative purification.
Attend this presentation to:
- Learn how to optimize your IP-RP analytical methods to improve resolution of your target product from closely related impurities.
- Understand how to simplify method translation from analytical to prep scale purification.
- Discover a simplified approach to oligonucleotide analysis and purification.
Key Learning Objectives:
- Understand the analytical challenges that make chromatographic analysis of oligos so demanding.
- Method development guidelines for analytical characterization of target oligonucleotide products.
- How to optimize lab scale oligo purification and scale up from Analytical to Prep.
Speakers:
Connor Flannery
Global Product Manager LC
Biocolumns
Agilent Technologies
Register Free: https://globalmeet.webcasts.com/starthere.jsp?ei=1583731&tp_key=528be5846d
Inside the Laboratory: The Richardson Group at the University of South Carolina
November 20th 2024In this edition of “Inside the Laboratory,” Susan Richardson of the University of South Carolina discusses her laboratory’s work with using electron ionization and chemical ionization with gas chromatography–mass spectrometry (GC–MS) to detect DBPs in complex environmental matrices, and how her work advances environmental analysis.
Critical Role of Oligonucleotides in Drug Development Highlighted at EAS Session
November 19th 2024A Monday session at the Eastern Analytical Symposium, sponsored by the Chinese American Chromatography Association, explored key challenges and solutions for achieving more sensitive oligonucleotide analysis.
RAFA 2024 Highlights: Cutting-Edge Chromatography Techniques for Food Safety and Food Analysis
November 18th 2024An illuminating session focusing on progress in analytical techniques used in food analysis took place on Wednesday 6 November 2024 at RAFA 2024 in Prague, The Czech Republic, including a talk on the analysis of 1000 toxins in 10 minutes.
RAFA 2024 Highlights: Contemporary Food Contamination Analysis Using Chromatography
November 18th 2024A series of lectures focusing on emerging analytical techniques used to analyse food contamination took place on Wednesday 6 November 2024 at RAFA 2024 in Prague, Czech Republic. The session included new approaches for analysing per- and polyfluoroalkyl substances (PFAS), polychlorinated alkanes (PCAS), Mineral Oil Hydrocarbons (MOH), and short- and medium-chain chlorinated paraffins (SCCPs and MCCPs).
