On November 16th, Agilent Technologies (Santa Clara, California) released their brand new, state-of-the-art, next gen chromatography data system (CDS), Agilent OpenLAB CDS.
On November 16th, Agilent Technologies (Santa Clara, California) released their brand new, state-of-the-art, next gen chromatography data system (CDS), Agilent OpenLAB CDS. The system features major improvements to Agilent’s current ChemStation and EZChrom Elite CDS platforms, and the new OpenLAB CDS is backward compatible with both of them.
“The new system is designed from a customer-centric perspective and dramatically improves productivity and quality across the entire customer organization -- from scientists and system administrators through lab managers and IT executives,” said Bruce von Herrmann, Vice President and General Manager of Agilent Software and Informatics.
“Our customers told us they wanted this new functionality without any changes to their existing workflows, and that's what we're delivering. We have engaged a number of customers throughout the design, development and testing phases of OpenLAB CDS,” Herrmann added.
OpenLAB supports both liquid and gas chromatographs from multiple different sources, enabling customers to have the freedom of choosing the vendor of their preference while also providing an easy way for labs to switch over from other data platforms.
According to the company, one of the major benefits of the new OpenLAB system is its intelligent reporting that allows users to generate analytical reports with whatever results they need and in any kind of format, enabling the reports to be precisely created to meet the needs of the user.
Analyzing Bone Proteins in Forensic Laboratories Using LC−MS/MS
November 4th 2024A recent study compared different workflows for extracting, purifying, and analyzing bone proteins using liquid chromatography with tandem mass spectrometry (LC–MS/MS), including an in-StageTip protocol previously optimized for forensic applications, and two protocols using novel suspension-trap technology (S-Trap) and different lysis solutions. LCGC International discussed this work with Noemi Procopio of the School of Law and Policing and the Research Centre for Field Archaeology and Forensic Taphonomy at the University of Central Lancashire (UK), corresponding author of the paper that resulted from this study.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
Profiling Volatile Organic Compounds in Whisky with GC×GC–MS
November 1st 2024Researchers from Austria, Greece, and Italy conducted a study to analyze volatile organic compounds (VOCs) present in Irish and Scotch whiskys using solid-phase microextraction (SPME) Arrow with comprehensive two-dimensional gas chromatography coupled to mass spectrometry (GC×GC–MS) to examine the organoleptic characteristics that influence the taste of spirits.