Afternoon Session: Advances in Liquid Chromatography I
This Monday afternoon session, which runs from 4:30 to 5:55 pm, will be kicked off by keynote lecturer Attila Felinger of the University of Pécs, in Hungary. Felinger will talk about reversed-flow liquid chromatography.
This Monday afternoon session, which runs from 4:30 to 5:55 p.m., will be kicked off by keynote lecturer Attila Felinger of the University of Pécs, in Hungary. Felinger will talk about reversed-flow liquid chromatography (LC).
Martin Gilar of Waters Corporation will follow, with a talk entitled, “What Can We Learn from Chromatographic Simulations?”
Oleg Krokhin of the University of Manitoba, in Winnepeg, Canada, will then talk about retention time predictions for peptides in strong anion-exchange HPLC, and the application of such predictions in two-dimensional LC–MS/MS separations that combine a strong anion-exchange step and a reversed-phase LC step.
The theme of computer tools will be carried on through the next talk, when Pankaj Aggarwal of Pfizer talks about the use of in silico tools for method development and robustness assessments of LC methods.
The session will wrap up with a talk by Ken Broeckhoven of the Free University of Brussels (Vrije Universiteit Brussel), who will address the question of where the limit of operating pressure lies in analytical scale liquid chromatography. In his work, Broeckhoven has demonstrated the use of very high operating pressure (up to 2600 bar) in ultrahigh-pressure LC (UHPLC).
The session will be chaired by Matthew Lauber of Waters Corporation.
Best of the Week: Food Analysis, Chemical Migration in Plastic Bottles, STEM Researcher of the Year
December 20th 2024Top articles published this week include the launch of our “From Lab to Table” content series, a Q&A interview about using liquid chromatography–high-resolution mass spectrometry (LC–HRMS) to assess chemical hazards in plastic bottles, and a piece recognizing Brett Paull for being named Tasmanian STEM Researcher of the Year.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
Determination of Pharmaceuticals by Capillary HPLC-MS/MS (Dec 2024)
December 19th 2024This application note demonstrates the use of a compact portable capillary liquid chromatograph, the Axcend Focus LC, coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis of pharmaceutical drugs in model aqueous samples.
