This Monday afternoon session, which runs from 4:30 to 5:55 pm, will be kicked off by keynote lecturer Attila Felinger of the University of Pécs, in Hungary. Felinger will talk about reversed-flow liquid chromatography.
This Monday afternoon session, which runs from 4:30 to 5:55 p.m., will be kicked off by keynote lecturer Attila Felinger of the University of Pécs, in Hungary. Felinger will talk about reversed-flow liquid chromatography (LC).
Martin Gilar of Waters Corporation will follow, with a talk entitled, “What Can We Learn from Chromatographic Simulations?”
Oleg Krokhin of the University of Manitoba, in Winnepeg, Canada, will then talk about retention time predictions for peptides in strong anion-exchange HPLC, and the application of such predictions in two-dimensional LC–MS/MS separations that combine a strong anion-exchange step and a reversed-phase LC step.
The theme of computer tools will be carried on through the next talk, when Pankaj Aggarwal of Pfizer talks about the use of in silico tools for method development and robustness assessments of LC methods.
The session will wrap up with a talk by Ken Broeckhoven of the Free University of Brussels (Vrije Universiteit Brussel), who will address the question of where the limit of operating pressure lies in analytical scale liquid chromatography. In his work, Broeckhoven has demonstrated the use of very high operating pressure (up to 2600 bar) in ultrahigh-pressure LC (UHPLC).
The session will be chaired by Matthew Lauber of Waters Corporation.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
Liquid Chromatography to Analyze Vitamin D Proteins in Psoriasis Patients
January 21st 2025Can a protein involved in delivering Vitamin D to target tissues have an altered serum profile in psoriasis patients with cardiovascular disease? Researchers used liquid chromatography (LC) to help find out.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
A Guide To Finding the Ideal Syringe and Needle
January 20th 2025Hamilton has produced a series of reference guides to assist science professionals in finding the best-suited products and configurations for their applications. The Syringe and Needle Reference Guide provides detailed information on Hamilton Company’s full portfolio of syringes and needles. Everything from cleaning and preventative maintenance to individual part numbers are available for review. It also includes selection charts to help you choose between syringe terminations like cemented needles and luer tips.