Advantar Laboratories Inc. has selected Waters? Empower 3 software to control its expanding portfolio of gas chromatography, high performance liquid chromatography and UPLC systems with advanced detectors including Waters? single and tandem quadrupole mass spectrometry, photodiode array and ultraviolet detectors.
Advantar Laboratories Inc. has selected Waters’ Empower 3 software to control its expanding portfolio of gas chromatography, high performance liquid chromatography and UPLC systems with advanced detectors including Waters’ single and tandem quadrupole mass spectrometry, photodiode array and ultraviolet detectors. The 21CFR Part 11 compliant-ready software will play an important role at Advantar and particularly with its new Method Remediation Services group.
“Our decision to go with Waters was driven by several key factors including requests from customers. By adding UPLC technology to our lab and creating the Method Remediation Services group, we can support clients who need to develop a UPLC method or rapidly convert multiple methods from HPLC to UPLC simultaneously for large and small molecules alike,” said Advantar Vice President of Sales & Marketing, Brandon Griffin.
“We strongly believe UPLC is the future of chromatography because it greatly reduces run times and solvent waste while significantly improving peak resolution, sensitivity and speed. These benefits translate into tremendous environmental, time and material cost savings for laboratories,” said Rohit Khanna, PhD, Vice President of Worldwide Marketing, Waters Division.
Advantar is now well equipped to support pharmaceutical companies and contract manufacturers of proprietary and/or off-patent drug products, by leveraging UPLC technology to enhance quality systems for time-critical release testing as well as method development/method transfer needs.
For more information, visit www.advantarlabs.com or ref="http://www.waters.com"target=*_blank">www.waters.com
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Metabolomics Analysis of Low Birth-Weight Infants Using UHPLC-MS/MS Following Lipid Emulsion
January 10th 2025A recent study aimed to directly compare the changes in serum metabolites among very low birth-rate (VLBW) infants following the administration of the soybean oil-based lipid emulsion and soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) lipid emulsion using untargeted metabolomics techniques.
Analyzing New Drug Modalities: An ISC 2024 Interview with Kelly Zhang
January 10th 2025At ISC 2024 in Liverpool, United Kingdom, LCGC International interviewed Kelly Zhang of Genentech about her work analyzing new drug modalities, such as mRNA, oligonucleotides, peptides, and cell and gene therapies.