Special Issues-03-01-2012

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Identification of Novel Psychoactive Substances Using Hyphenated Mass Spectrometric Techniques

Suzanne Fergus;Sulaf Assi;Jacqueline L. Stair

March 1st 2012

Gas chromatography–mass spectrometry (GC–MS) and liquid chromatography–mass spectrometry (LC–MS) techniques offer advantages in separating and confirming the identity of constituents in novel psychoactive substances.

Accurate Mass: Why It's the Best Solution for Metabolite Identification in Discovery, Development, and Clinical Applications

Phillip R. Tiller

March 1st 2012

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Accurate-mass approaches offer a significant advance over nominal-mass approaches in the arena of qualitative analysis, and some of the analytical approaches can now be conducted in a relatively routine manner.

The Use of Mass-Spectrometry-Based Proteomics for Reliable Detection and Identification of Pathogens as Illustrated by the Study of Bee Colony Collapse Disorder

Charles H. Wick

March 1st 2012

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A study of colony collapse disorder in honey bees illustrates how mass spectrometry–based proteomics techniques can be used to to identify pathogens without any prior knowledge of what is contained in the sample.