Characterizing Reversed-Phase Column Selectivity
Guest authors Lloyd Snyder and John Dolan describe a method for determining reversed-phase column selectivity.
A Compendium of GC Terms and Techniques
John Hinshaw updates his glossary of GC terms and techniques.
Preparative Chromatography with Improved Loadability
The authors show that the loadability and throughput of ionizable compounds can be enhanced by using hybrid packings.
Determination of Aroclor 1248 in Rat Plasma and Liver Matrices: Recovery and Quantification Considerations
The author determines the uncertainty in the quantification of four rat liver samples by applying a statistical evaluation.
Requirements for Validating a Capillary Isoelectric Focusing Method for Impurity Quantitation
The guest authors present a strategy for validating a capillary isoelectric focusing method intended to quantitate impurities in a protein drug substance.
Mobile-Phase Buffers, Part I — The Interpretation of pH in Partially Aqueous Mobile Phases
Guest author G. William Tindall discusses pH measurements in aqueous solutions and the changes that occur when organic solvent is added.