May 17th 2024
Here are the top five articles that the editors of LCGC International published this week.
Advances in Liquid Chromatography for Mustard Agent Exposure Biomonitoring Revealed
October 10th 2023Valérie Pichon's review in Analytical and Bioanalytical Chemistry delves into sophisticated liquid chromatography techniques for detecting albumin adducts, vital biomarkers in retrospective mustard agent exposure monitoring, offering a broader window of detection than urine-based methods.
New 2D LC–MS Analytical Method Unveils the Secrets of Ancient Chinese Herbal Formula HGWD
October 10th 2023A comprehensive analytical approach utilizing online two-dimensional liquid chromatography coupled with hybrid linear ion trap orbital trap mass spectrometry, has enabled the in-depth analysis of Huangqi Guizhi Wuwu decoction, identifying 170 chemical constituents and offering insights into its complex chemical composition and potential therapeutic properties.
Why is Open-Access Hyphenation Important for Chromatographers?
October 4th 2023At HPLC 2023, John Langley, a professor at the University of Southampton in Southampton, UK, presented a talk called "(R)evolution of Hyphenations, Through Open-Access RP-HPLC–MS, Open-Access UHPSFC–MS and 2D-LC–IMS-MS in Academia". He spoke with LCGC on the importance of open-access hyphenation, and how to implement it in your research.
Scientists used supercritical fluid chromatography (SFC) and ultrahigh-pressure liquid chromatography (UHPLC)—both coupled with high-resolution mass spectrometry (HRMS)—to analyze various types of chlorinated paraffins (CPs) in fish oil-based dietary supplements.
Multitargeted Internal Calibration Using LC–MS Quantifies Chronic Kidney Disease-Linked Metabolites
September 30th 2023Researchers have developed a multitargeted internal calibration method for precise quantification of chronic kidney disease (CKD)-related endogenous metabolites using liquid chromatography–mass spectrometry (LC–MS).
Review of Portable X-ray Fluorescence in Analysis Applications for Solid and Liquid Food Samples
September 10th 2023This report not only focused on the different types of portable X-ray fluorescence (pXRF) spectrometers available, but also their capacities for limits of detection and quantification (LOD and LOQ, respectively), linearity, and calibration strategies.