Application Notes: Chiral

Daicel Chiral Technologies' unique HPLC and SFC chiral stationary phases are capable of separating the most challenging compounds, like the atropisomers of Sotorasib.

Application note demonstrating the improved chiral separation of herbicide mecoprop by use of an immobilized column that allows usage of a wider range of solvents

This application note demonstrates how the use of DCM in particular had a dramatic effect on the separation and afforded conditions that could be further adapted to a preparative scale application.

Mirtazapine is an approved antidepressant, with other studies exploring its use to treat sleep apnea, substance abuse withdrawal symptoms, and as an antihistamine.

Discover a reliable and robust HPLC method to separate Δ10-THC and Δ6a,10a-THC isomers produced from Δ9-THC degradation using a chiral HPLC stationary phase.

Daicel’s CHIRALPAK® IJ gives access to an expanded range of solvents, which yields new separations not previously achievable on the coated CHIRALCEL® OJ.

This application note demonstrates the ability of Daicel’s CHIRALPAK® IA-3 to perform both chiral and achiral separations using SFC and hydrobenzoin as a test compound.

DAICEL’s CHIRALPAK® sub-2 µm columns yield sub 30-second chiral separations of Thalidomide and Naproxen under SFC conditions.

Multi-attribute analysis combines protein A affinity chromatography, SEC, and LC/MS in a 3D setup for assessment of features including mAb titer and size variants.

Multi-attribute analysis combines protein A affinity chromatography, SEC, and LC/MS in a 3D setup for assessment of features including mAb titer and size variants.