May 16th 2024
Scientists from the Lunan Pharmaceutical Group explored the use of UHPLC-MS/MS to test the effects of Shouhui Tongbian capsules (SHTBs) on slow transit constipation (STC).
New Method Developed to Map Cellulose Ether Monomer Composition
May 2nd 2023A new RPLC–MS method can map the substitution degree and composition of β-glucose monomers of cellulose ethers (CEs), providing detailed compositional distributions and constitutional isomer distributions, thereby identifying compositional variation between bio-stable and non-bio-stable CEs and unexpected methylations in EHEC samples.
Exploring Biopharmaceutical Analysis with Compact Capillary Liquid Chromatography Instrumentation
A recent trend in the design of LC instrumentation is the move towards miniaturized and portable systems.
Event: Emerging Separations Technologies 2023
May 1st 2023The Chromatographic Society and the Separations Science Group of the Analytical Division of the Royal Society of Chemistry are pleased to announce Emerging Separations Technologies 2023 is to be held 24–25 May 2023, at RSC Burlington House, London, UK.
An LC–MS/MS Method for the Evaluation of Intestinal Permeability in Blood Plasma
May 1st 2023A rapid and robust LC–MS/MS method for determining lactulose and rhamnose concentrations in blood plasma was used to determine intestinal permeability from blood plasma, which can help diagnose gastrointestinal diseases such as Crohn’s disease.
LCE and LCA: Suspect Screening of Lupin-Produced Phytotoxins in Environmental Samples
April 30th 2023Selective pressurized liquid extraction and multilayer solid‑phase extraction methods are described for high‑throughput plant, soil, and water sample preparations. Optimal analytical conditions are described for the improvement of detection sensitivities and coverage. A Source Supported Suspect Screening (4S) approach is described; phytotoxins detected in the source plant were used to improve the identification of phytotoxins in soil and water.
Poisoned Chalice: Study Reveals Impact of Transformed Landscapes on Carnivores and Environment
April 10th 2023By performing tissue analysis of caracals in captivity and in their natural African habitats, scientists were able to quantify uptake of toxic chemicals from the environment depending on how polluted they are.