May 16th 2024
Scientists from the Lunan Pharmaceutical Group explored the use of UHPLC-MS/MS to test the effects of Shouhui Tongbian capsules (SHTBs) on slow transit constipation (STC).
Synthesizing Synthetic Oligonucleotides: An Interview with the CEO of Oligo Factory
January 15th 2024LCGC and Spectroscopy Editor Patrick Lavery spoke with Oligo Factory CEO Chris Boggess about the company’s recently attained compliance with Good Manufacturing Practice (GMP) International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) Expert Working Group (Q7) guidance and its distinction from Research Use Only (RUO) and International Organization for Standardization (ISO) 13485 designations.
Inside the Laboratory: The McCall Group at San Diego State University
January 8th 2024In our first edition of “Inside the Laboratory,” Laura-Isobel McCall, PhD, an associate professor of chemistry at San Diego State University, discusses her group’s most recent work using “chemical cartography” in order to perform effective liquid chromatography–mass spectrometry (LC–MS) data acquisition.
Machine Learning Models Help Researchers Predict the Ages of Ginseng
November 9th 2023To combat fraudulent sales of low-aged ginseng disguised as high-aged ginseng, scientists from Shanghai University of Traditional Chinese Medicine created machine learning models to predict the ages of ginseng samples.
LC and Green Chemistry Advancements in Lenvatinib Stability Testing and Environmental Responsibility
October 23rd 2023A novel lenvatinib stability-indicating method, developed through a quality by design (QbD) approach and embracing principles of green chemistry, offers a robust solution for ensuring the drug's stability under various conditions.
HPLC and LC–MS Estimation of Goserelin Acetate Sustained-Release Implant Impurity
October 21st 2023Researchers have developed a meticulous method for analyzing impurities in a product used for early treatment of breast cancer in premenopausal and perimenopausal women, shedding light on the product’s degradation pathways.